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Product Line: Pharmaceutical Chemicals

Microcrystalline Cellulose

CAS 9004-34-6

Molecular structure of Microcrystalline Cellulose

CAS · 9004-34-6

01

Product Overview

Microcrystalline Cellulose (MCC) | CAS 9004-34-6 is a purified, partially depolymerized cellulose derived from natural plant fibers. Widely utilized across the pharmaceutical, food, and cosmetic industries, MCC is renowned for its versatility as a functional excipient. With its unique properties, MCC enhances product performance and quality in a variety of applications.

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Product Specifications

Property Specification
Grade PH 101/USP 40
Appearance White or similar white, fine or granular powder
Assay 97% to 102%
Polymerization 350 max
Granulometry Remains 60 mesh <1%, remains 200 mesh >30%
Conductivity 75 µS/cm max
pH Value 5.0 to 7.5
Loss on Drying 7.0% max
Residue on Ignition 0.1% max
Water Soluble Substance 0.25% max
Ether-Soluble Substances 0.05% max
Heavy Metal 10 ppm max
Total Aerobic Microbial Count (TAMC) 1000 cfu/g max
Total Yeast and Mold Count (TYMC) 100 cfu/g max
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Applications

1. Pharmaceutical Industry:

- Tablet and Capsule Formulations: Microcrystalline cellulose is commonly used as a binder and filler in tablet and capsule manufacturing. Its excellent compressibility allows for strong, durable tablets produced via direct compression or wet granulation techniques.

- Controlled-Release Systems: Microcrystalline Cellulose can be used in controlled-release formulations, ensuring the consistent and gradual release of active ingredients.

2. Food Industry:

- Food Additive: Microcrystalline cellulose serves as an anti-caking agent, stabilizer, and texturizer in food products, improving texture, shelf life, and consistency.

- Calorie Reduction: As a fat substitute, MCC is included in low-calorie foods to enhance mouthfeel without adding significant calories.

3. Cosmetics and Personal Care:

- Thickener and Stabilizer: In creams, lotions, and other cosmetic formulations, MCC acts as a stabilizer and thickening agent, providing desirable texture and consistency.

- Exfoliating Agent: Its granular form is sometimes incorporated into skincare products for gentle exfoliation.

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Benefits

1. Exceptional Binding Properties:

- Microcrystalline Cellulose provides robust binding in tablet formulations, ensuring the production of high-quality tablets that maintain their structural integrity during handling and storage.

2. Versatility in Formulations:

- It is compatible with a wide range of active pharmaceutical ingredients (APIs) and excipients, allowing formulators to create diverse product types across industries.

3. Enhanced Stability:

- Microcrystalline cellulose is chemically stable, non-reactive, and resistant to moisture, making it an excellent choice for formulations requiring long-term stability.

4. Improved Product Performance:

- In addition to its role as a binder and filler, MCC improves the disintegration and dissolution rates of tablets, contributing to the bioavailability of active ingredients.

5. Safe and Non-Toxic:

- MCC is recognized as safe (GRAS) by regulatory authorities, ensuring consumer confidence and compliance with global standards.

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Conclusion

A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.