CAS · 26348-70-9
Product Overview
Methyl L-lysinate dihydrochloride is a high-purity amino-acids supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White to off-white powder |
|---|---|
| IR Spectrum | In accordance with structure |
| Specific Rotation [α]D20 | +21.0 ± 2.5° (C=1, MeOH) |
| Assay | 98.5%–102.0% |
Applications
Methyl L-lysinate dihydrochloride (CAS 26348-70-9) is a protected amino acid derivative widely used in peptide synthesis and medicinal chemistry. It serves as a building block for the stepwise assembly of peptides, allowing selective incorporation of lysine residues with protected amino functionality. The dihydrochloride salt form improves stability and solubility in polar solvents, making it suitable for solid-phase and solution-phase peptide synthesis. It is also applied in the preparation of modified peptides, peptidomimetics, and pharmaceutical intermediates, where precise control over amino acid incorporation is critical. Additionally, it is used in research and chemical biology to study protein interactions, enzyme activity, and structure–activity relationships of bioactive peptides.
Benefits
The benefits of Methyl L-lysinate dihydrochloride stem from its chemical stability, stereochemical integrity, and ease of handling. The methyl ester protects the carboxyl group while the dihydrochloride ensures solubility and reduces hygroscopicity, allowing accurate dosing in peptide synthesis. Its high optical purity guarantees correct L-configuration incorporation, which is crucial for maintaining peptide bioactivity and conformation. The compound is compatible with standard coupling reagents and peptide synthesis protocols, enabling high yields and reproducibility. These features make it a reliable intermediate for developing complex peptides, biologically active compounds, and peptide-based drug candidates.
Conclusion
Methyl L-lysinate dihydrochloride is a valuable amino acid derivative for peptide synthesis and medicinal chemistry. Its protected functionality, stability, and stereochemical purity allow precise incorporation into peptides and bioactive molecules. By supporting efficient synthesis and reproducible results, it remains an essential building block for research, peptide development, and pharmaceutical applications.
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