CAS · 41489-76-3
Product Overview
Methyl 5-formyl-2-hydroxybenzoate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White solid |
|---|---|
| Purity (GC): | 98% min |
| HNMR: | Confirms |
| Loss on drying: | 1% max |
| Water content: | 1% max |
Applications
Methyl 5-formyl-2-hydroxybenzoate is a versatile aromatic aldehyde widely used in organic synthesis, pharmaceuticals, and chemical research. It serves as a key intermediate for the synthesis of bioactive compounds, including anti-inflammatory, antioxidant, and antimicrobial agents. In medicinal chemistry, it is employed in constructing heterocyclic systems, Schiff bases, and polyphenolic derivatives for drug discovery and structure-activity relationship (SAR) studies. Additionally, the compound is used in the preparation of dyes, pigments, and polymer additives, where its hydroxyl and ester functionalities enable further functionalization. Its aldehyde group also allows participation in condensation, oxidation, and reduction reactions, making it a valuable building block for complex molecular architectures.
Benefits
The combination of hydroxyl, formyl, and ester groups provides multiple reactive sites, allowing selective chemical modifications and efficient synthesis of diverse derivatives. Its hydroxyl group enhances solubility and reactivity, while the formyl functionality enables condensation reactions with amines and hydrazides, facilitating the formation of Schiff bases and heterocycles. The ester group allows further transformations, such as hydrolysis or amidation, broadening its synthetic utility. Additionally, the compound is stable under standard laboratory conditions and compatible with various organic solvents, making it a reliable and reproducible intermediate for both laboratory-scale and industrial-scale applications.
Conclusion
Methyl 5-formyl-2-hydroxybenzoate is a highly functionalized aromatic aldehyde with broad applications in pharmaceuticals, organic synthesis, and material science. Its multiple reactive groups allow the construction of bioactive molecules, heterocycles, and functional materials with precision and efficiency. With its chemical versatility, stability, and synthetic potential, this compound remains an essential intermediate for medicinal chemistry research and advanced chemical development.
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