CAS · 147116-67-4
Product Overview
Maropitant is a high-purity veterinary-medicine supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Property | Specification |
|---|---|
| Appearance | White to off white solid |
| Purity | 99% min |
| Chirality Purity | 99% min |
| Identification by IR | Retention time complies |
| Identification by HPLC | Corresponds to the reference spectrum |
| Single Impurity | 0.2% max |
| Total Impurities | 1% max |
| Heavy Metal | 20 ppm max |
| Residue on Ignition | 0.1% max |
| LOD (Loss on Drying) | 0.5% max |
| Ethanol (Solvent Residue) | 5000 ppm max |
| Toluene (Solvent Residue) | 890 ppm max |
Applications
1. Antiemetic in Dogs and Cats
● Used to prevent and treat vomiting due to:
Motion sickness
Acute gastroenteritis
Postoperative nausea
Chemotherapy-induced vomiting
● Acts centrally by inhibiting the neurokinin-1 (NK1) receptor in the vomiting center of the brainstem, which blocks the action of substance P.
2. Prevention of Motion Sickness
● Given orally 2 hours before travel to prevent vomiting associated with motion sickness in dogs.
● Demonstrated efficacy with minimal sedation, making it preferable to older antihistamines or phenothiazines.
3. Supportive Care in Cancer Therapy
● Used off-label to prevent vomiting caused by chemotherapy in veterinary oncology.
● Improves tolerance to treatment and quality of life in animals undergoing aggressive therapies.
4. Postoperative Recovery
● Reduces nausea and vomiting after anesthesia and surgery, promoting quicker recovery and appetite return.
Benefits
1. Highly Effective and Fast-Acting
● Works within 1–2 hours of administration.
● One of the few antiemetics that blocks both central and peripheral pathways of vomiting.
2. Well-Tolerated
● Safe for use in dogs aged 8 weeks and older and cats aged 16 weeks and older.
● Minimal side effects, with mild injection site pain being the most commonly reported issue for injectable forms.
3. Non-Sedating
● Unlike older anti-nausea drugs (e.g., diphenhydramine), Maropitant does not cause drowsiness, making it suitable for active pets.
4. Multiple Administration Routes
● Available as oral tablets and injectable formulations, allowing flexibility in treatment.
● Injectable form is useful for vomiting animals unable to take oral medication.
Conclusion
A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.