CAS · 15687-27-1
Product Overview
Ibuprofen is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Grade | EP11 grade |
|---|---|
| Appearance | White to off-white crystal powder |
| Assay | 98.5–101% |
| Solubility | Confirm |
| Identification | Confirm |
| Solution | Clear and colorless |
| Optical rotation | -0.05 to +0.05 deg |
| Melting point | 75–78 °C |
| Loss on drying | 0.5% max |
| Sulphated ash | 0.1% max |
| Related substances – Impurity A | 0.05% max |
| Related substances – Impurity B | 0.05% max |
| Related substances – Impurity N | 0.15% max |
| Other unknown single impurity | 0.05% max |
| Total impurity | 0.2% max |
| Residual solvent – Petroleum ether | 250 ppm max |
| Residual solvent – Toluene | 3000 ppm max |
| Residual solvent – Methanol | 890 ppm max |
| Bulk density | 0.15–0.40 g/ml |
| Tapped density | 0.35–0.60 g/ml |
Applications
Ibuprofen is widely used as a nonsteroidal anti-inflammatory drug in pharmaceutical and healthcare settings. It is commonly administered for the management of mild to moderate pain, inflammation, and fever associated with conditions such as headaches, dental pain, musculoskeletal injuries, arthritis, and dysmenorrhea. Ibuprofen is formulated into a variety of dosage forms, including tablets, capsules, suspensions, topical gels, and injectable preparations, enabling flexible use across different patient populations. Beyond clinical use, ibuprofen is also utilized in pharmaceutical research and development as a reference compound for evaluating anti-inflammatory and analgesic activity, bioavailability, and formulation performance. Its chemical structure is studied in medicinal chemistry for the development of improved nonsteroidal anti-inflammatory agents and related therapeutic compounds.
Benefits
Ibuprofen offers several advantages due to its well-established efficacy, safety profile, and versatility. It works by inhibiting cyclooxygenase enzymes involved in prostaglandin synthesis, leading to effective reduction of pain, inflammation, and fever. The compound demonstrates rapid onset of action and reliable symptom relief when used at recommended doses. Ibuprofen is generally well tolerated and suitable for both short-term and long-term use in appropriate patients. Its availability in multiple formulations supports convenient dosing and improved patient compliance. Additionally, the compound is chemically stable and amenable to large-scale manufacturing, ensuring consistent quality and widespread accessibility.
Conclusion
Ibuprofen is a widely used and essential nonsteroidal anti-inflammatory drug with broad applications in pain relief, inflammation control, and fever reduction. Its benefits, including proven efficacy, versatility in formulation, and favorable safety profile, make it a cornerstone therapy in modern medicine. The compound continues to play a significant role in clinical treatment, pharmaceutical research, and the development of improved anti-inflammatory therapies.
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