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Product Line: Pharmaceutical Chemicals

Hypromellose

CAS 9004-65-3

Molecular structure of Hypromellose

CAS · 9004-65-3

01

Product Overview

Hypromellose丨CAS 9004-65-3, also known as hydroxypropyl methylcellulose (HPMC), is a versatile and widely used polymer in various industries, including pharmaceuticals, cosmetics, and food. Its multifunctional properties make it a valuable ingredient in formulations that require controlled release, thickening, emulsification, or stabilization.

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Product Specifications

Property Specification
Appearance White to off white fibrous or granular powder
Identification A to E Conforms
Methoxy 19%-24%
Hydroxypropoxy 4%-12%
Viscosity 3000~5600 mPa.s
Loss on drying 5.0% max
Residue on ignition 1.5% max
pH 5-8
Bacterium 1000 cfu/g max
Mold 1000 cfu/g max
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Applications

1. Pharmaceutical Industry:

- Film Coating: HPMC is a preferred film-forming agent used for coating tablets and capsules, offering a protective barrier that improves product stability and appearance.

- Controlled Release Formulations: As a hydrophilic matrix-forming agent, HPMC is used in controlled and sustained-release drug delivery systems, ensuring steady drug release over time.

- Suspending Agent: It acts as a suspending agent in liquid formulations, helping maintain uniform dispersion of active ingredients.

2. Food Industry:

- Thickening and Stabilization: HPMC is used as a thickener, stabilizer, and emulsifier in various food products, improving texture and consistency.

- Vegetarian Gelatin Alternative: It serves as a substitute for animal-derived gelatin in capsule shells and other applications, catering to vegetarian and vegan preferences.

3. Cosmetic Industry:

- Personal Care Products: HPMC is commonly used in shampoos, lotions, and creams as a thickener and emulsifier, enhancing the viscosity and texture of formulations.

- Film Forming: Its film-forming capability helps in products like facial masks and hair gels, providing desired functional and aesthetic properties.

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Benefits

1. Versatility in Formulation:

- Wide Compatibility: HPMC is compatible with a broad range of active ingredients and excipients, making it an ideal choice for diverse applications.

- Customizable Properties: It is available in various grades with differing viscosity levels and substitution ratios, allowing formulators to tailor its functionality to specific needs.

2. Enhanced Product Stability:

- Protective Barrier: In pharmaceuticals, HPMC coatings protect tablets from moisture and oxidation, prolonging shelf life.

- Thermal Stability: It exhibits excellent stability under a range of temperatures, ensuring consistent performance in diverse conditions.

3. Improved Bioavailability:

- Controlled Release: HPMC ensures predictable and controlled drug release, enhancing therapeutic outcomes and reducing side effects.

4. Eco-Friendly and Biodegradable:

- Sustainability: As a cellulose derivative, HPMC is plant-based and biodegradable, aligning with growing demands for environmentally responsible materials.

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Conclusion

A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.