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Product Line: Pharmaceutical Chemicals

gamma-Cyclodextrin

CAS 17465-86-0

Molecular structure of gamma-Cyclodextrin

CAS · 17465-86-0

01

Product Overview

gamma-Cyclodextrin is a high-purity cyclodextrin-derivatives supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance: White to off-white powder
Content: 98% min
Residue on ignition: 0.1% max
Reducing sugar: 0.5% max
Heavy metals: 5 ppm max
Pb: 0.5 ppm max
As: 1.3 ppm max
Residue on solvents: 20 ppm max
Water content: 11.0% max
Specific rotation: +173° to +180°
Total number of bacterial colony: 1000 CFU/g max
Coliform group: 40 MPN/g max
Mold: 25 CFU/g max
Yeast: 25 CFU/g max
Pathogens in 25g: Absence
03

Applications

1. Pharmaceuticals

Drug Solubilizer & Stabilizer: Improves solubility and bioavailability of poorly water-soluble drugs through inclusion complexation.

Controlled Release Agent: Provides sustained or targeted drug delivery, especially for oral, nasal, and injectable formulations.

Taste Masking: Encapsulates bitter or unpleasant-tasting drugs.

Stabilization: Enhances thermal and photostability of drugs and biologics (e.g., peptides, steroids, vitamins).

2. Food Industry

Flavor Encapsulation: Traps volatile aroma and flavor molecules, preventing degradation and extending shelf life.

Cholesterol Removal: Used in dairy and egg processing to selectively remove cholesterol without affecting taste or nutrition.

Carrier for Nutrients: Improves dispersibility and stability of fat-soluble vitamins (e.g., A, D, E, K) and antioxidants.

Dietary Fiber & Prebiotic: Considered safe and digestible in small amounts, supporting gut health.

3. Cosmetics & Personal Care

Fragrance Stabilization: Protects and prolongs the release of volatile fragrance ingredients.

Active Ingredient Delivery: Enhances the penetration and efficacy of active cosmetic agents like retinoids or botanical extracts.

Improved Texture: Can help control viscosity and reduce stickiness in formulations.

4. Environmental & Industrial Uses

Pollutant Removal: Forms complexes with organic pollutants, pesticides, and heavy metals in environmental remediation.

Green Solvent System: Used in catalysis and chemical separations due to its biodegradable, non-toxic profile.

Textile & Polymer Applications: Used in smart materials to enable controlled release of fragrances or antimicrobial agents.

04

Benefits

Feature

Benefit

Large Cavity Size

Can accommodate larger molecules than α- or β-cyclodextrins.

High Aqueous Solubility

Greater than β-CD, making it suitable for water-based systems.

Low Toxicity and Biodegradability

Safe for human consumption (GRAS in the U.S. for some uses) and environmentally friendly.

Improved Bioavailability

Enables better absorption of lipophilic drugs or nutrients.

Versatility

Useful in a wide range of industries, from medicine to cosmetics to food science.

05

Conclusion

gamma-Cyclodextrin丨CAS 17465-86-0 is a biocompatible, water-soluble, and high-capacity encapsulating agent that supports applications across pharmaceuticals, food technology, cosmetics, and environmental science. Its large cavity size and excellent safety profile make it a valuable ingredient for improving the performance, safety, and stability of a wide range of products.

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Beta-Cyclodextrin Methyl Ethers丨CAS 128446-36-6