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Molecular structure of Furacilin

CAS · 59-87-0

01

Product Overview

Furacilin is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Grade: EP11.0
Characters: Yellow or brownish-yellow crystal powder, very slightly soluble in water, slightly soluble in ethanol (96%)
Identification A (EP): The ratio of absorbance at 375 nm to 260 nm is 1.15 to 1.30
Identification B (EP): Infrared absorption spectrum matches nitrofural CRS
Identification C (EP): Principal spot in chromatogram matches reference solution
Identification D (EP): A violet-red colour is produced
pH (EP): 5.0–7.0
Loss on drying (EP): 0.5% max
Sulphated ash (EP): 0.1% max
Related substances (HPLC) (EP): 1,2-bis[(5-nitrofuran-2-yl)methylen]diazane: 0.5% max (5-nitrofuran-2-yl)methylene diacetate: 0.5% max Any unspecified impurity: 0.1% max Total impurities: 1.0% max
Assay (UV) (EP): 97.0%–103.0% of C6H6N4O4 (on dried basis)
Residual Acetic acid: 1000 ppm max
03

Applications

 

1. Topical Antiseptic in Human Medicine

Used in the treatment and prevention of:

Superficial wounds and abrasions

Skin ulcers

Burns

Surgical incisions

Bacterial skin infections

2. Mucosal and Eye Infections

Applied as irrigating solutions, ointments, or eye drops for:

Conjunctivitis

Sinus infections

Otitis externa (ear infections)

3. Veterinary Applications

Widely used in animal health for:

Treating infected wounds and skin infections

Promoting healing in surgical sites or injuries

Fish farming (aquaculture) to prevent bacterial diseases

4. Hydrotherapy and Wet Dressings

Dissolved in sterile water for wound irrigation and dressings in hospital settings, particularly for burn victims.

04

Benefits

 

✅ Broad-Spectrum Antibacterial Activity

Effective against both Gram-positive and Gram-negative bacteria, including:

Staphylococcus aureus

Escherichia coli

Streptococcus pyogenes

Proteus species

✅ Low Resistance Development

Works by damaging bacterial DNA and enzymes, which reduces the likelihood of resistance compared to some antibiotics.

✅ Anti-inflammatory Properties

Helps reduce localized inflammation in wounds and infections, aiding faster recovery.

✅ Promotes Healing

Supports tissue regeneration and prevents secondary infection in chronic or non-healing wounds.

✅ Versatile Formulations

Available in multiple forms:

Ointments and creams

Aqueous or alcoholic solutions

Powders for reconstitution

Eye drops or ear drops

✅ Cost-Effective and Widely Available

Economical choice for healthcare providers, especially in developing countries.

05

Conclusion

Furacilin (CAS 59-87-0) remains a trusted topical antimicrobial agent with long-standing use in medicine and veterinary care. Its broad-spectrum activity, low resistance profile, and wound-healing benefits make it especially valuable in resource-limited healthcare settings and as a first-line topical antiseptic in clinical and home environments. Responsible use ensures continued effectiveness and safety.

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