Ertapenem Sodium

Ertapenem Sodium is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

1. Treatment of Complicated Infections

Ertapenem Sodium丨CAS 153773-82-1 is FDA-approved and commonly used for treating:

● Complicated intra-abdominal infections

● Complicated urinary tract infections (UTIs)

● Skin and skin structure infections

● Acute pelvic infections

● Community-acquired pneumonia (CAP)

● Complicated gynecological infections

2. Prophylaxis in Colorectal Surgery

It is sometimes used as a single-dose preoperative prophylaxis in elective colorectal surgery to prevent postoperative infection due to its long half-life and wide coverage.

3. Hospital-Acquired and Resistant Pathogens

While not effective against Pseudomonas aeruginosa and Acinetobacter, it is highly effective against ESBL-producing Enterobacteriaceae, making it valuable for empirical therapy in resistant bacterial infections.

4. Once-Daily Dosing in Outpatient Settings

Due to its long half-life (~4 hours) and once-daily administration, Ertapenem is suitable for Outpatient Parenteral Antibiotic Therapy (OPAT), reducing hospital stays and healthcare costs.

✅ Broad Spectrum of Activity

● Active against a wide range of Gram-positive and Gram-negative bacteria, anaerobes, and β-lactamase producers.

● Covers many multi-drug resistant (MDR) organisms (excluding non-fermenters like P. aeruginosa).

✅ Convenient Dosing

● Once-daily intravenous (IV) or intramuscular (IM) administration makes it user-friendly and reduces caregiver burden.

✅ Effective Against ESBL-Producing Strains

● Ertapenem is often a drug of choice for infections caused by extended-spectrum β-lactamase (ESBL) producing bacteria.

✅ High Tissue Penetration

● Demonstrates excellent distribution in tissues, including peritoneal fluid, gynecologic tissues, and skin.

✅ Stable Against Most β-lactamases

● Remains effective where many penicillins and cephalosporins fail due to enzyme resistance.

Ertapenem Sodium丨CAS 153773-82-1 is a powerful, broad-spectrum antibiotic ideal for the treatment of various complicated bacterial infections. Its convenient once-daily dosing, robust activity against resistant pathogens, and broad clinical utility make it a cornerstone in both hospital and outpatient infection management. With proper stewardship, it remains a vital weapon against multidrug-resistant bacteria.

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