CAS · 471-53-4
Product Overview
Enoxolone is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Grade: | EP9.0 |
|---|---|
| Appearance: | White or almost white hygroscopic powder |
| Assay (Potentiometry): | 98.0% to 101.0% |
| Identification: | |
| Infrared absorption: | Complies |
| Thin-Layer Chromatography: | Complies |
| Color reaction: | Pink colour |
| Appearance of solution: | Clear and not more intensely coloured than reference solution Y6 |
| Heavy metals: | 20 ppm max. |
| Loss on drying: | 0.5% max. |
| Sulphated ash: | 0.2% max. |
| Related substances: | |
| Total impurities: | 2.0% max. |
| Any impurity: | 0.7% max. |
| Specific Optical Rotation (dried substance): | +145° to 154° |
Applications
1. Pharmaceutical Industry
Enoxolone is widely used for its anti-inflammatory and antiviral activities. It is an active ingredient in topical formulations for skin conditions such as eczema, psoriasis, and dermatitis. It also shows potential in treating viral infections, including herpes simplex.
2. Cosmetics and Personal Care
Used as a soothing and anti-irritant agent in skincare products, Enoxolone helps reduce redness, irritation, and inflammation. It is commonly included in creams, lotions, and after-sun products.
3. Oral Health Products
In oral care, Enoxolone is incorporated into mouthwashes and toothpastes for its anti-inflammatory and antimicrobial properties, helping to manage gingivitis and other inflammatory oral conditions.
4. Nutraceuticals and Functional Foods
Derived from licorice, Enoxolone is studied for its potential benefits in digestive health and as an immune system modulator.
Benefits
Anti-inflammatory: Reduces inflammation by inhibiting enzymes such as 11β-hydroxysteroid dehydrogenase, which modulates corticosteroid activity.
Antiviral: Exhibits inhibitory effects against various viruses, aiding in the management of viral infections.
Skin Soothing: Provides relief from itching, redness, and irritation, making it valuable in dermatological and cosmetic products.
Antimicrobial: Shows activity against certain bacteria and fungi, supporting oral and skin health.
Natural Origin: Derived from licorice root, appealing to the growing demand for plant-based bioactives.
Conclusion
Enoxolone (glycyrrhetinic acid) is a bioactive triterpenoid with significant anti-inflammatory, antiviral, and soothing properties. Its multifunctional benefits have made it a staple ingredient in pharmaceutical, cosmetic, oral care, and nutraceutical products. With its natural origin and broad range of applications, Enoxolone continues to be a valuable compound in the development of products aimed at improving skin health, managing inflammation, and supporting immune function.
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