CAS · 84294-96-2
Product Overview
Enoxacin is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Off-white to slightly yellow crystalline powder |
|---|---|
| Purity(HPLC) | 98% min |
| Assay | 98.5~102% |
| HNMR | conforms |
| Related substances | 1% max |
| Loss on Drying | 7.8~9% |
| Residue on ignition | 0.1% max |
Applications
Enoxacin is a second-generation fluoroquinolone antibiotic widely used in the treatment of bacterial infections. It is effective against a broad spectrum of Gram-negative and some Gram-positive bacteria, making it suitable for urinary tract infections, respiratory tract infections, and gastrointestinal infections. Enoxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. In addition to its clinical use, Enoxacin is applied in pharmaceutical research for studying antimicrobial mechanisms, resistance development, and structure–activity relationships in the design of next-generation fluoroquinolone derivatives.
Benefits
The benefits of Enoxacin include its broad-spectrum antibacterial activity, high oral bioavailability, and relatively low risk of cross-resistance with other antibiotic classes. Its ability to inhibit bacterial DNA replication effectively results in rapid bactericidal action. Enoxacin is generally well-tolerated and demonstrates predictable pharmacokinetics, allowing convenient oral dosing. Additionally, its potency against both Gram-negative and certain Gram-positive bacteria makes it versatile in treating mixed infections. In research, its well-characterized mode of action provides a valuable reference compound for developing improved fluoroquinolone antibiotics with enhanced efficacy and safety profiles.
Conclusion
Enoxacin is a clinically important fluoroquinolone antibiotic with broad-spectrum activity and a well-defined mechanism of action. Its effective inhibition of bacterial DNA gyrase and topoisomerase IV, combined with high oral bioavailability and tolerability, makes it a valuable option for treating various bacterial infections. Beyond clinical use, Enoxacin serves as a key compound in antimicrobial research and the development of novel fluoroquinolone derivatives, contributing to advances in infection management and drug discovery.
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