CAS · 1809-20-7
Product Overview
Diisopropyl phosphite is a high-purity pesticide-intermediate supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Colorless to light yellow transparent liquid |
|---|---|
| Assay: | 98% min |
| Refractive index: | 1.4960-1.4980 |
| Density (25℃): | 0.997 |
| Each impurity: | 0.5% max |
| Water: | 0.5% max |
Applications
1. Intermediate in Organophosphorus Chemistry
Used extensively as a key intermediate in the synthesis of various organophosphorus compounds including:
Phosphonates
Phosphinates
Phosphoramidates
Important for the preparation of phosphorus-containing ligands and catalysts.
2. Agricultural Chemicals
Employed in the synthesis of pesticides, herbicides, and fungicides that contain phosphorus moieties.
Useful in preparing active ingredients with biocidal activity.
3. Pharmaceutical Synthesis
Used as a building block in the synthesis of phosphorus-containing drugs and enzyme inhibitors.
Enables the formation of phosphonate analogs of biologically active molecules.
4. Chemical Reagent in Organic Synthesis
Utilized in various phosphonate ester synthesis reactions, such as the Arbuzov reaction and Michaelis–Arbuzov rearrangement.
Serves as a reagent for phosphorylation of alcohols or amines.
Benefits
1. High Reactivity and Selectivity
The diisopropyl ester groups offer a good balance of reactivity and stability, enabling selective reactions with other functional groups.
2. Good Solubility and Handling
Liquid at room temperature with good solubility in common organic solvents, making it easy to handle and incorporate into synthesis protocols.
3. Versatile Building Block
Provides access to a wide variety of phosphorus-containing compounds through substitution and rearrangement reactions.
4. Improved Safety Profile
Compared to other phosphites, diisopropyl phosphite is relatively stable and less prone to oxidation, improving safety during storage and use.
Conclusion
Diisopropyl Phosphite (CAS 1809-20-7) is a valuable reagent and intermediate in organophosphorus chemistry, widely used for synthesizing phosphonates, pharmaceuticals, and agrochemicals. Its favorable reactivity profile, ease of handling, and versatility make it essential in both academic research and industrial chemical synthesis.
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