CAS · 115144-35-9
Product Overview
D-Luciferin potassium salt is a high-purity fluorescein supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Light yellow to yellow powder |
|---|---|
| Purity (HPLC): | 99% min |
| Solubility: | 30mg/ml min |
| Loss on drying: | 1.0% max |
| MS: | Conforms to structure |
| HNMR: | Conforms to structure |
Applications
1. In Vivo and In Vitro Bioluminescent Imaging
Widely used in live animal imaging to monitor biological processes such as tumor growth, infection progression, and gene expression.
The potassium salt form offers improved solubility and stability, ideal for intravenous or intraperitoneal injections in animal models.
2. Reporter Gene Assays
Serves as a substrate in luciferase-based reporter systems for studying gene regulation, cell signaling, and transcriptional activity.
The enhanced solubility improves assay reproducibility and sensitivity.
3. High-Throughput Screening
Applied in drug discovery platforms to assess enzyme activity, cell viability, and compound effects with bioluminescent readouts.
4. Biosensor Development
Used in biosensors detecting ATP or other analytes where bioluminescence indicates target presence or enzymatic activity.
Benefits
1. Enhanced Water Solubility
Potassium salt form dissolves readily in aqueous buffers, facilitating consistent dosing and improved bioavailability.
2. Improved Stability
More chemically stable than free acid, allowing for longer shelf life and better handling during experiments.
3. High Sensitivity
Retains the high sensitivity and specificity of the D-Luciferin-luciferase reaction, producing bright bioluminescent signals with low background noise.
4. Non-Invasive Real-Time Monitoring
Supports non-invasive, longitudinal studies of biological events in living organisms, enabling dynamic tracking.
5. Versatile Compatibility
Compatible with various luciferase enzymes and cell types across research models.
Conclusion
D-Luciferin potassium salt (CAS 115144-35-9) is a water-soluble, stable form of the bioluminescent substrate D-Luciferin. It is widely used for bioluminescent imaging, gene reporter assays, drug screening, and biosensor applications. Its enhanced solubility and stability make it particularly useful for in vivo animal studies and high-throughput assays, providing researchers with reliable and sensitive tools for studying biological processes in real time.
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