CAS · 78782-17-9
Product Overview
Bis(pinacolato)borylmethane is a high-purity borane supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | white to off white solid |
|---|---|
| Purity (GC) | 98% min |
| Water (KF) | 0.5% max |
Applications
Bis(pinacolato)borylmethane is widely used in organic synthesis and pharmaceutical research as a versatile boron-containing building block. It serves as a key reagent in Suzuki–Miyaura cross-coupling reactions, enabling the formation of carbon–carbon bonds in the synthesis of biaryl, heteroaryl, and alkyl-substituted compounds. The compound is also applied in the preparation of functionalized boronates, medicinal chemistry intermediates, and complex organic molecules for drug discovery. In materials science, it is used to construct boron-functionalized polymers and small molecules with unique electronic or optical properties. Additionally, Bis(pinacolato)borylmethane is employed in academic research to study organoboron reactivity, stereoselective transformations, and new methodologies for carbon–carbon bond formation.
Benefits
Bis(pinacolato)borylmethane offers several advantages that enhance its utility in chemical synthesis and research. Its pinacolato-protected boronate provides stability, ease of handling, and resistance to hydrolysis, allowing reliable storage and reproducible reactions. The compound's reactivity in cross-coupling and other carbon–carbon bond-forming reactions enables efficient access to complex molecules and diverse chemical libraries. Its versatility allows selective functionalization under mild conditions, supporting multi-step synthetic pathways without compromising sensitive groups. Additionally, it facilitates rapid exploration of structure–activity relationships in medicinal chemistry and the development of boron-containing materials with tunable properties.
Conclusion
Bis(pinacolato)borylmethane is a valuable organoboron reagent with applications in pharmaceutical synthesis, organic chemistry, and materials research. Its stability, reactivity, and versatility make it an essential building block for carbon–carbon bond formation and functionalized molecule development. Overall, Bis(pinacolato)borylmethane supports efficient synthesis, molecular diversification, and innovation in both industrial and academic chemical research.
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