CAS · 5928-66-5
Product Overview
Benzoin, (-)- is a high-purity essences-and-fragrances supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White solid |
|---|---|
| Purity (HPLC) | 98% min |
Applications
(-)-Benzoin is a chiral hydroxy ketone widely used in organic synthesis, pharmaceuticals, and asymmetric catalysis. It serves as a key intermediate for the preparation of α-hydroxy ketones, chiral ligands, and optically active compounds. In medicinal chemistry, (-)-benzoin is used for the synthesis of biologically active molecules, including antiviral, antibacterial, and anticancer agents. It is also applied in asymmetric reactions, such as the benzoin condensation, where it acts as a nucleophilic catalyst or a chiral building block for producing enantioenriched products. Additionally, (-)-benzoin finds use in fragrance and flavor industries due to its aromatic character, contributing to certain synthetic perfumes and flavors.
Benefits
The benefits of (-)-benzoin lie in its chirality, reactivity, and versatility. Its optically active hydroxy ketone functionality allows enantioselective transformations, enabling the production of chiral intermediates and fine chemicals with high stereochemical control. The hydroxyl and carbonyl groups provide reactive sites for diverse chemical modifications, supporting multi-step synthetic strategies. Its stability under standard laboratory conditions and compatibility with common solvents enhance handling and usability. Overall, (-)-benzoin provides a reliable platform for both research and industrial-scale asymmetric synthesis, improving selectivity and efficiency.
Conclusion
(-)-Benzoin is a valuable chiral intermediate for asymmetric synthesis, pharmaceutical development, and fine chemical production. Its combination of optical activity, reactive functional groups, and versatility enables enantioselective reactions and the synthesis of bioactive molecules. By facilitating controlled and efficient chemical transformations, (-)-benzoin remains an essential building block in modern organic and medicinal chemistry.
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