CAS · 126824-24-6
Product Overview
BAPTA tetrasodium salt hydrate is a high-purity analytical-reagents supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Off-white powder |
|---|---|
| Purity (HPLC) | 97% min |
| Loss on drying | 5% max |
Applications
BAPTA tetrasodium salt hydrate is primarily used in biological and biochemical research to regulate and buffer intracellular calcium levels. In cell biology experiments, it is used to study calcium-dependent signaling pathways, enzyme activation, neurotransmitter release, and muscle contraction mechanisms. The compound is often applied in in vitro biochemical assays and cell culture experiments where precise control of calcium ion concentration is required. In neuroscience research, BAPTA derivatives are widely used to investigate synaptic transmission and neuronal signaling processes. It is also used in electrophysiology studies to prevent unwanted calcium fluctuations that may interfere with experimental measurements. In addition, BAPTA-based compounds are frequently incorporated into fluorescent calcium indicator systems and calcium buffering solutions used in laboratory research.
Benefits
One of the major advantages of BAPTA tetrasodium salt hydrate is its strong and selective binding affinity for calcium ions compared with other metal ions such as magnesium. This selectivity allows researchers to control calcium-dependent reactions without significantly affecting other biological processes. The tetrasodium salt form significantly improves water solubility, allowing easy preparation of aqueous buffer solutions for laboratory use. BAPTA also has relatively fast calcium-binding kinetics, making it particularly useful for experiments that involve rapid calcium signaling events. Additionally, its chemical structure minimizes interference with many biological molecules, helping maintain accurate experimental conditions. These properties make it a reliable reagent for studying cellular physiology and biochemical pathways involving calcium regulation.
Conclusion
BAPTA tetrasodium salt hydrate is an important calcium-chelating reagent widely used in biochemical, cellular, and physiological research. Its high selectivity for calcium ions, excellent water solubility, and rapid binding kinetics make it a valuable tool for investigating calcium-dependent biological processes. As calcium signaling continues to be a central focus in biomedical research, BAPTA derivatives remain essential reagents in modern life science laboratories.
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