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Product Line: Life Science

Arginine oxoglurate

CAS 16856-18-1

Molecular structure of Arginine oxoglurate

CAS · 16856-18-1

01

Product Overview

Arginine oxoglurate is a high-purity amino-acid supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Item Specification
Appearance White to yellow crystalline powder
Assay 98% to 102.0%
L-Arginine 65.5% to 69%
Alpha Ketoglutarate 26.5% to 29%
Identification HPLC
Specific Rotation [α]D20 (8g/100ml, 6N HCl) +16.5° to +18.5°
pH (10% H2O) 5.5 to 7.0
Hydrate Max 6.8%
Chloride Max 0.05%
Loss on Drying Max 1.0%
Residue on Ignition Max 0.2%
Heavy Metals Max 10 ppm
Lead (Pb) Max 0.3 ppm
Arsenic (As) Max 1 ppm
Cadmium (Cd) Max 1 ppm
Mercury (Hg) Max 0.1 ppm
Iron Max 10 ppm
Bulk Density Min 0.5 g/ml
Particle Size Thus 30
Total Plate Count Max 1000 cfu/g
Yeast Max 100 cfu/g
Mold Max 100 cfu/g
E. Coli Negative
Salmonella Negative
Staphylococcus Aureus Negative
Melamine and Melamine Derivatives Free
03

Applications

1. Sports and Fitness Nutrition

Arginine oxoglutarate is a popular ingredient in pre-workout supplements and performance-enhancing formulations, due to its combined ability to:

● Enhance nitric oxide (NO) production

● Promote vasodilation, improving blood flow and muscle pump

● Support muscle growth, recovery, and endurance

Key Applications:

● Bodybuilding supplements

● Endurance sports nutrition

● Recovery drinks or powders

2. Medical and Clinical Nutrition

Arginine oxoglutarate has also been studied and used in clinical settings, especially in:

● Post-surgical recovery

● Wound healing

● Critical care nutrition

In these contexts, it helps:

● Improve tissue perfusion

● Support protein synthesis

● Reduce muscle catabolism

It is included in some parenteral nutrition formulas and enteral nutrition products for trauma, burn, and surgical patients.

3. Cardiovascular and Endothelial Health

Due to its vasodilatory effects via enhanced nitric oxide synthesis, Arginine oxoglurate丨CAS 16856-18-1 is explored for supporting:

● Healthy blood pressure

● Endothelial function

● Cardiovascular wellness

Although more research is needed, its NO-mediated benefits suggest potential utility in managing mild hypertension or circulatory dysfunctions.

4. Metabolic and Anti-Catabolic Support

Alpha-ketoglutarate (AKG), part of the compound, plays a key role in:

● Energy metabolism via the Krebs cycle

● Nitrogen scavenging

● Inhibiting protein breakdown

This makes AAKG valuable in conditions where muscle wasting, stress-induced catabolism, or energy deficiency are issues.

5. Biochemical and Research Use

Arginine oxoglutarate is used in biochemical studies related to:

● Amino acid metabolism

● Nitric oxide pathways

● Mitochondrial energetics

● Signal transduction in muscle and endothelial cells

It is also evaluated in research on nutrigenomics and metabolic disease interventions.

04

Benefits

1. Enhanced Nitric Oxide Production

● Arginine is a direct precursor of nitric oxide (NO), a molecule that:
Promotes vasodilation
Enhances oxygen and nutrient delivery
Reduces vascular resistance

By improving blood flow to tissues, AAKG may enhance exercise performance, recovery, and tissue oxygenation.

2. Supports Muscle Growth and Performance

● L-Arginine increases growth hormone release and protein synthesis, while AKG supports amino acid metabolism.

● Together, they may:
Enhance anabolism
Reduce muscle breakdown
Support lean muscle mass maintenance

This synergy is particularly useful in athletes and individuals undergoing rehabilitation or intense training.

3. Accelerates Healing and Recovery

● Arginine and AKG work to improve collagen synthesis, wound healing, and cell regeneration, especially in:
Surgical recovery
Burn and trauma care
Pressure ulcer management

This benefit is especially important in elderly or critically ill patients where healing is compromised.

4. Metabolic Fuel and Antioxidant Support

● AKG acts as a key intermediate in the citric acid cycle, supporting cellular energy production.

● It may also reduce ammonia toxicity and enhance glutamine availability, particularly under metabolic stress or catabolic states.

5. Supports Immune Function

Arginine oxoglurate丨CAS 16856-18-1 plays a role in T-cell function, wound immune response, and cytokine regulation, making AAKG beneficial in:

● Immunonutrition

● Infection recovery

● Malnutrition-related immune deficiency

Conclusion

Arginine oxoglurate丨CAS 16856-18-1 is a multi-functional compound with applications in sports nutrition, clinical therapy, and metabolic research. Its unique synergy-combining arginine's NO-enhancing effects with alpha-ketoglutarate's metabolic and anti-catabolic functions-offers substantial benefits in promoting:

● Muscle performance and recovery

● Tissue repair and healing

● Cardiovascular support

● Energy metabolism and immunity

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05

Conclusion

A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.