7-Methoxy-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-(1,3)oxazino(3,2-d)pyrido(1,2-a)pyrazine-9-carboxylic acid, (4R,12AS)-
CAS 1335210-34-8
CAS · 1335210-34-8
Product Overview
7-Methoxy-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-(1,3)oxazino(3,2-d)pyrido(1,2-a)pyrazine-9-carboxylic acid, (4R,12AS)- is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White to light-yellow solid |
|---|---|
| Purity (HPLC): | 98% min |
| Single largest impurity: | 1.0% max |
| Loss on drying: | 0.5% max |
Applications
This compound is a complex heterocyclic molecule primarily used as an intermediate in pharmaceutical research and drug development. Its multi-ring structure, including oxazine, pyrido, and pyrazine motifs, makes it suitable for the synthesis of bioactive compounds, particularly those targeting bacterial or viral enzymes, or other therapeutic proteins. It is employed in medicinal chemistry to explore structure-activity relationships (SAR) and to develop novel drug candidates with enhanced potency, selectivity, and pharmacokinetic properties. Additionally, it serves as a building block for the preparation of analogs and derivatives for preclinical studies.
Benefits
The compound's rigid, multifunctional heterocyclic structure provides high chemical and stereochemical stability, enabling precise derivatization and selective functionalization. The presence of carboxylic acid, methoxy, and keto groups allows for diverse chemical transformations, such as amide coupling, esterification, and nucleophilic substitution, facilitating the creation of a wide range of derivatives. Its defined stereochemistry ensures consistent biological activity, making it highly valuable in drug design and synthetic optimization. The molecule's structural complexity allows it to mimic or interact with biological targets effectively, supporting advanced medicinal chemistry research.
Conclusion
This heterocyclic carboxylic acid is a valuable intermediate for pharmaceutical development, enabling the synthesis of complex, bioactive molecules. Its multifunctional groups, rigid stereochemistry, and chemical stability make it indispensable for drug discovery, SAR studies, and the development of novel therapeutics with improved efficacy and selectivity.
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