7-Bromobenzo[b]furan

7-Bromobenzo[b]furan is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

7-Bromobenzo[b]furan (CAS 133720-60-2) is a heteroaromatic compound widely used as a key intermediate in organic synthesis, particularly in pharmaceutical and materials chemistry. The bromine substituent makes it well suited for cross-coupling reactions such as Suzuki, Heck, and Sonogashira couplings, enabling the construction of more complex benzo[b]furan derivatives. These derivatives are frequently explored in drug discovery programs, agrochemical development, and the synthesis of bioactive small molecules. In addition, 7-bromobenzo[b]furan is used in the preparation of functional materials, including organic semiconductors, OLED-related intermediates, and advanced aromatic systems where the benzo[b]furan core contributes to electronic and optical properties. It is also applied in academic and industrial research focused on heterocycle chemistry and structure–activity relationship studies.

The benefits of 7-bromobenzo[b]furan stem from its high synthetic versatility, well-defined heteroaromatic structure, and reactivity in metal-catalyzed transformations. The bromine atom provides a reliable handle for selective functionalization, allowing efficient introduction of diverse substituents under mild conditions. The benzo[b]furan ring system offers rigidity and conjugation, which are valuable for tuning biological activity and electronic behavior in target molecules. The compound is generally stable under standard storage and reaction conditions and is compatible with a wide range of solvents and catalysts. These features enable reproducible synthesis, high structural diversity, and efficient route development in pharmaceutical and materials research.

7-Bromobenzo[b]furan is a valuable heteroaromatic intermediate for pharmaceutical, agrochemical, and materials chemistry applications. Its brominated benzo[b]furan core allows efficient cross-coupling and structural modification, supporting the development of bioactive molecules and functional materials. By offering reactivity, stability, and design flexibility, 7-bromobenzo[b]furan remains an important building block in modern synthetic chemistry.

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