CAS · 58759-63-0
Product Overview
5-Nitro-2-benzothiazolethiol is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Pale yellow crystals |
|---|---|
| Purity (HPLC) | 96% min |
| Water Content | 1% max |
Applications
5-Nitro-2-benzothiazolethiol (CAS 58759-63-0) is a sulfur- and nitrogen-containing heterocyclic compound widely used as an intermediate in pharmaceutical, agrochemical, and fine chemical synthesis. Its benzothiazole core and thiol group make it a versatile building block for the synthesis of bioactive molecules, including antimicrobial, antifungal, and anticancer agents. It is also employed in medicinal chemistry for developing enzyme inhibitors, receptor modulators, and other therapeutic candidates. Beyond pharmaceuticals, it is used in the preparation of heterocyclic derivatives, dyes, and specialty chemicals, as well as in research focused on creating novel sulfur-containing heterocycles with unique chemical and biological properties.
Benefits
The benefits of 5-Nitro-2-benzothiazolethiol stem from its reactive thiol and nitro-substituted benzothiazole scaffold. The thiol group allows for nucleophilic reactions, disulfide formation, and metal coordination, facilitating selective derivatization and incorporation into more complex molecules. The nitro group enhances electron-withdrawing character, which can improve reactivity and regioselectivity in synthetic transformations. Its structural rigidity, chemical stability, and compatibility with common organic solvents make it convenient for laboratory-scale synthesis and industrial applications. These properties enable the efficient production of functional derivatives, improving both synthetic yield and biological relevance.
Conclusion
5-Nitro-2-benzothiazolethiol is a versatile heterocyclic intermediate with broad applications in pharmaceutical, agrochemical, and specialty chemical synthesis. Its thiol functionality and nitro-substituted benzothiazole core allow selective derivatization, enabling the creation of bioactive molecules and functional heterocycles. By supporting the development of antimicrobial, anticancer, and other therapeutic compounds, it remains an important reagent in both research and industrial chemistry.
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