5-Bromoindanone

5-Bromoindanone is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

1. Organic Synthesis Intermediate

Building Block for Pharmaceuticals and Fine Chemicals:

5-Bromoindanone is used as a key intermediate in the synthesis of various biologically active compounds, including pharmaceuticals, agrochemicals, and dyes.

Halogen Functionalization:

The bromine substituent enables further functionalization through cross-coupling reactions such as Suzuki, Heck, or Sonogashira couplings to attach diverse groups.

Precursor to Indanone Derivatives:

Used to prepare substituted indanones which serve as scaffolds in medicinal chemistry for drug development.

2. Medicinal Chemistry

Synthesis of Neuroactive Agents:

Indanone derivatives are often studied for their potential in neuropharmacology, including as enzyme inhibitors or receptor ligands.

Design of Anti-inflammatory and Anticancer Agents:

Functionalized indanones have shown bioactivities, and 5-bromo substitution allows for elaboration to optimize activity.

3. Material Science

Organic Electronics and Photonics:

Indanone derivatives have potential use in organic semiconductors, dyes, and fluorescent materials, and 5-bromo substitution allows for fine-tuning electronic properties.

Versatile Halogen Handle:

The bromine at position 5 is a reactive site for palladium-catalyzed cross-coupling, facilitating rapid derivatization.

Stable Intermediate:

Solid form with good shelf stability makes it easy to handle and store.

Facilitates Complex Molecule Construction:

Enables introduction of diverse functional groups while maintaining the indanone core.

5-Bromoindanone (CAS 34598-49-7) is a valuable intermediate in synthetic organic chemistry, particularly in pharmaceutical and material sciences. Its bromine substituent allows versatile chemical transformations, making it a useful starting material for developing new drugs, agrochemicals, and functional organic materials. Its stability and reactivity make it a popular choice for researchers aiming to synthesize substituted indanone derivatives efficiently.

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