CAS · 156772-63-3
Product Overview
5-bromo-2-fluoropyridin-2-ol is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Light white powder |
|---|---|
| Water: | 0.5% max |
| Assay by GC: | 98% min |
Applications
5-Bromo-2-fluoropyridin-2-ol (CAS 156772-63-3) is a halogenated pyridin-2-ol derivative that serves as a versatile intermediate in organic synthesis and pharmaceutical research. Its structure, containing both bromine and fluorine substituents on the pyridine ring, provides high reactivity for cross-coupling reactions, nucleophilic substitutions, and heterocyclic transformations. It is widely used in the synthesis of bioactive compounds, including pharmaceutical intermediates, agrochemicals, and specialty heterocycles. In medicinal chemistry, it enables the development of molecules with enhanced metabolic stability, lipophilicity, and target specificity due to the presence of halogen atoms. Additionally, it is employed in academic and industrial research for the construction of functionalized heteroaromatic compounds, facilitating the exploration of new chemical scaffolds for drug discovery and advanced materials.
Benefits
The benefits of 5-bromo-2-fluoropyridin-2-ol arise from its high chemical versatility and the advantageous properties imparted by its halogen substituents. The bromine atom allows for efficient palladium-catalyzed cross-coupling reactions, supporting the rapid assembly of complex molecular architectures. The fluorine atom enhances the stability and lipophilicity of target molecules, improving pharmacokinetic properties in drug candidates. Its pyridin-2-ol core contributes to hydrogen bonding and coordination capabilities, which are valuable in designing biologically active compounds and ligands. These properties make it an essential building block for synthetic chemists aiming to develop novel pharmaceuticals, agrochemicals, and functional heterocyclic molecules.
Conclusion
In conclusion, 5-bromo-2-fluoropyridin-2-ol is a highly functional halogenated pyridine derivative that plays a key role in pharmaceutical, agrochemical, and chemical research. Its unique combination of reactivity, stability, and functional versatility enables the efficient synthesis of bioactive molecules and advanced heterocyclic compounds. By supporting innovation in drug discovery, materials science, and synthetic chemistry, it remains a valuable intermediate for both applied and exploratory research.
Previous
Next