5-Amino-2,4-di-tert-butylphenylmethylcarbonate
CAS 1182822-31-6
CAS · 1182822-31-6
Product Overview
5-Amino-2,4-di-tert-butylphenylmethylcarbonate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Off-white powder |
|---|---|
| Assay (on dried basis) | 98% min |
| Identification by NMR | To match with the reference standard |
| Individual Impurity by HPLC | 0.5% max |
| Total impurities by HPLC | 1% max |
| Residue on Ignition | 0.5% max |
| Loss on drying | 0.5% max |
Applications
5-Amino-2,4-di-tert-butylphenylmethylcarbonate (CAS 1182822-31-6) is a functionalized aromatic carbonate primarily used as an intermediate in pharmaceutical, agrochemical, and fine chemical synthesis. Its structure, featuring an amino group, bulky tert-butyl substituents, and a carbonate moiety, makes it valuable for preparing protected amines, substituted aromatic derivatives, and carbamate-containing molecules. In medicinal chemistry, it is applied in the synthesis of drug candidates where steric protection and functional group stability are required. In agrochemical research, it serves as a building block for herbicides, fungicides, and insecticides with enhanced chemical stability. Additionally, it is utilized in organic synthesis research for developing novel carbamate-based intermediates and functionalized phenolic derivatives.
Benefits
The benefits of 5-amino-2,4-di-tert-butylphenylmethylcarbonate arise from its multifunctional reactivity and steric protection. The amino group enables selective derivatization through acylation, alkylation, or condensation reactions, while the tert-butyl groups provide steric hindrance that enhances chemical stability and reduces side reactions. The carbonate moiety allows for controlled deprotection or coupling under mild conditions, making it a versatile intermediate for multi-step syntheses. Its structural design ensures high selectivity, improved yield, and compatibility with sensitive reaction conditions, supporting efficient synthesis of complex molecules in pharmaceutical and agrochemical development.
Conclusion
In summary, 5-amino-2,4-di-tert-butylphenylmethylcarbonate is a valuable intermediate for pharmaceutical, agrochemical, and fine chemical synthesis. Its applications include building protected amines, carbamate derivatives, and functionalized aromatic compounds, while its benefits lie in steric protection, selective reactivity, and compatibility with complex synthetic sequences. As modern chemical synthesis increasingly requires stable and multifunctional intermediates, this compound serves as a practical and reliable tool for advancing innovative molecule design.
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