5-(4-Bromophenyl)furfural

5-(4-Bromophenyl)furfural is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

5-(4-Bromophenyl)furfural (CAS 20005-42-9) is a highly functionalized aldehyde used extensively in organic synthesis, medicinal chemistry, and materials science. Its structure, which combines a furan ring with a bromophenyl moiety and an aldehyde group, makes it an ideal building block for cross-coupling reactions such as Suzuki–Miyaura or Heck reactions. This enables the construction of complex biaryl or heteroaryl compounds, which are valuable in the development of pharmaceuticals, agrochemicals, and bioactive molecules. Additionally, it is used in the synthesis of conjugated materials, dyes, and fluorescent compounds, where the combination of the furan and aromatic systems contributes to enhanced electronic and optical properties.

The benefits of 5-(4-Bromophenyl)furfural arise from its multifunctional reactivity and chemical versatility. The aldehyde group allows for condensation, reductive amination, and nucleophilic addition reactions, while the bromine atom facilitates selective cross-coupling and functionalization. Its furan ring contributes to electron-rich aromatic character, enhancing reactivity in electrophilic substitution and cyclization reactions. The compound is chemically stable under standard storage conditions and soluble in common organic solvents, making it convenient for laboratory and industrial-scale synthesis. Its bifunctional nature enables efficient construction of complex molecular architectures with high selectivity and reproducibility.

5-(4-Bromophenyl)furfural is a versatile intermediate that bridges organic synthesis, medicinal chemistry, and materials science. Its combination of an aldehyde, bromophenyl, and furan moiety provides multiple reactive sites, facilitating the creation of bioactive molecules, advanced materials, and functional derivatives. By enabling selective and efficient synthetic transformations, this compound remains a valuable tool in both research and industrial applications.

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