CAS · 29968-78-3
Product Overview
4-Nitrophenethylamine hydrochloride is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Description | Off-white to pale yellow crystal powder |
|---|---|
| Purity (HPLC) | 99.5% min |
| Identification | Retention time (RT) of the main peak in the chromatogram of sample in assay test should match with that of reference standard |
| Total Impurity | 0.5% max |
| Single Impurity | 0.1% max |
| Water | 1.0% max |
Applications
4-Nitrophenethylamine hydrochloride is a functionalized aromatic amine that finds extensive use as an intermediate in organic synthesis and pharmaceutical research. Its primary application lies in the development of bioactive molecules, where the nitro group serves as a versatile site for chemical modification, including reduction to an amine or participation in substitution reactions. It is often employed in the synthesis of pharmaceutical intermediates, particularly in the design of central nervous system agents, enzyme inhibitors, and receptor-targeted compounds. Additionally, it is used in chemical research for preparing dyes, specialty chemicals, and functionalized building blocks in medicinal chemistry. The compound's hydrochloride form enhances its stability and solubility, making it convenient for laboratory handling and facilitating reproducible reactions in multi-step synthetic processes.
Benefits
The benefits of 4-Nitrophenethylamine hydrochloride are linked to its chemical reactivity, stability, and versatility as a synthetic intermediate. The nitro group provides a functional handle for a wide range of chemical transformations, enabling the production of diverse derivatives with tailored biological or physicochemical properties. Its amine functionality allows for the formation of amides, Schiff bases, and other nitrogen-containing compounds, which are central to drug development and chemical research. The hydrochloride salt form enhances water solubility, improving its handling and incorporation in aqueous or polar reaction systems. By offering a stable, reactive, and versatile platform, this compound facilitates efficient synthesis of novel molecules, supports medicinal chemistry optimization, and contributes to research in enzyme modulation, receptor targeting, and functional material design.
Conclusion
4-Nitrophenethylamine hydrochloride is a valuable intermediate with wide-ranging applications in pharmaceutical synthesis, chemical research, and material science. Its dual functional groups-the nitro and amine moieties-provide extensive opportunities for chemical modification, enabling the design of novel compounds with enhanced biological or chemical properties. The compound's stability and solubility make it practical for laboratory use and large-scale synthesis. Overall, 4-Nitrophenethylamine hydrochloride is an important building block that supports innovation in drug discovery, specialty chemical production, and synthetic organic research.
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