CAS · 6068-72-0
Product Overview
4-Cyanobenzoyl chloride is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White to beige solid |
|---|---|
| 4-Cyanobenzoyl chloride (GC) | 98% min |
| Sum of active species (GC) | 99% min |
| 3-Cyanobenzoyl chloride (GC) | 0.1% max |
| Terephthaloyl chloride (GC) | 0.2% max |
Applications
4-Cyanobenzoyl chloride is a highly reactive organic intermediate widely used in pharmaceutical, agrochemical, and specialty chemical synthesis. It serves as an important acylating agent in the preparation of amides, esters, and other functionalized derivatives. In medicinal chemistry, it is used to introduce the 4-cyanobenzoyl moiety into molecules, facilitating the development of bioactive compounds, including enzyme inhibitors, receptor modulators, and anti-inflammatory agents. It is also applied in the synthesis of dyes, polymers, and liquid crystals, where the cyano group provides specific electronic and structural properties. Additionally, 4-cyanobenzoyl chloride is valuable in research laboratories for the preparation of advanced intermediates in multi-step organic synthesis.
Benefits
4-Cyanobenzoyl chloride offers several advantages due to its high reactivity, selectivity, and compatibility with a variety of nucleophiles. Its electrophilic acyl chloride group allows efficient formation of amides and esters under controlled conditions, enabling high-yield reactions. The para-cyano substituent provides additional versatility, enhancing the chemical and physical properties of target molecules. It is stable under dry, anhydrous conditions, ensuring reproducibility in laboratory and industrial syntheses. Furthermore, its well-defined structure allows for predictable reactivity, making it a reliable reagent for medicinal chemistry and material science applications.
Conclusion
4-Cyanobenzoyl chloride is a valuable chemical intermediate with broad applications in pharmaceuticals, agrochemicals, and specialty materials. Its benefits, including high reactivity, selectivity, stability, and versatility in functional group modification, make it an essential tool for efficient synthesis of bioactive molecules, polymers, and advanced chemical intermediates. Continued use of this compound supports innovation in drug development, material design, and multi-step organic synthesis.
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