CAS · 214360-73-3
Product Overview
4-Aminophenylboronic acid pinacol ester is a high-purity oled-materials supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | light yellow powder |
|---|---|
| Purity (HPLC) | 99.5% min |
| Melting Point | 169.0 ~ 173.0 °C |
Applications
4-Aminophenylboronic acid pinacol ester is widely used as a key intermediate in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds. It is valuable in the synthesis of pharmaceuticals, agrochemicals, and functional materials, including biologically active molecules and complex organic frameworks. This compound also serves as a building block for the preparation of boron-containing polymers and sensors. In medicinal chemistry, it is used to develop enzyme inhibitors, especially proteasome inhibitors and other boron-based therapeutics.
Benefits
The boronic ester functionality enables efficient and selective cross-coupling under mild conditions, facilitating the rapid assembly of complex molecules with high yields. The amino group provides an additional site for chemical modification, enhancing molecular diversity and enabling further functionalization. Its stability and ease of handling make it convenient for large-scale synthesis. Furthermore, the compound's role in producing boron-containing drugs highlights its importance in targeted therapy development, benefiting pharmaceutical innovation.
Conclusion
4-Aminophenylboronic acid pinacol ester is a versatile and powerful synthetic intermediate essential for modern organic synthesis and drug discovery. Its dual functional groups allow for broad chemical transformations, making it a critical tool in developing advanced materials and pharmaceuticals with high efficiency and selectivity.
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