CAS · 51-36-5
Product Overview
3,5-Dichlorobenzoic acid is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White powder |
|---|---|
| Assay | 98% min |
| Water | 1% max |
Applications
3,5-Dichlorobenzoic acid (CAS 51-36-5) is a halogenated aromatic carboxylic acid widely used as an intermediate in organic synthesis, pharmaceuticals, and agrochemicals. It serves as a building block for the preparation of herbicides, fungicides, and other agrochemical agents where the dichloro substitution pattern enhances bioactivity and stability. In pharmaceutical chemistry, it is employed in the synthesis of anti-inflammatory, antimicrobial, and anticancer compounds, often serving as a precursor for amides, esters, and heterocyclic derivatives. Additionally, 3,5-dichlorobenzoic acid is used in materials science for the preparation of functionalized polymers, dyes, and ligands in coordination chemistry. Its reactive carboxylic acid group allows coupling, esterification, and amidation reactions, making it versatile for multi-step synthesis.
Benefits
The benefits of 3,5-dichlorobenzoic acid arise from its dichloro-substituted aromatic structure and reactive carboxyl functionality. The chlorine atoms enhance electron-withdrawing effects, improving chemical stability, reactivity, and selectivity in synthetic transformations. The carboxylic acid group enables efficient formation of esters, amides, and salts, supporting diverse chemical modifications. Its solid, crystalline form provides ease of handling, storage stability, and compatibility with standard organic solvents and reagents. Additionally, the dichloro motif often improves the lipophilicity, metabolic stability, and bioactivity of derivatives in agrochemical and pharmaceutical applications, making it a valuable intermediate.
Conclusion
3,5-Dichlorobenzoic acid is a versatile and reactive intermediate with applications in pharmaceuticals, agrochemicals, and materials science. Its combination of a dichloro-substituted aromatic ring and carboxyl group enables selective derivatization and the synthesis of biologically active molecules, functional polymers, and advanced materials. By supporting the efficient construction of high-value compounds, it remains an important building block in research and industrial chemistry.
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