3-(Dimethylamino)-1-(thiophen-2-yl)propan-1-one hydrochloride
CAS 5424-47-5
CAS · 5424-47-5
Product Overview
3-(Dimethylamino)-1-(thiophen-2-yl)propan-1-one hydrochloride is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White crystalline powder |
|---|---|
| Assay: | 98.0%～102.0% |
| Identification: | IR, UV conform |
| Water: | 1% max |
| Residue on ignition: | 0.2% max |
| Heavy metals: | 0.002% max |
| Related substances: | |
| Total impurity: | 1% max |
| Individual: | 0.2% max |
Applications
1. Pharmaceutical Intermediate
Used as an intermediate in the synthesis of various pharmaceutical compounds, especially those containing thiophene and amino ketone functionalities.
Important in the development of drugs targeting the central nervous system (CNS) and other therapeutic areas.
2. Organic Synthesis
Serves as a versatile building block for the construction of heterocyclic compounds and other complex molecules.
The presence of both an amino and ketone group allows for diverse chemical transformations, such as condensations and substitutions.
3. Research and Development
Used in medicinal chemistry research to create new molecules with potential biological activities.
Valuable for structure-activity relationship (SAR) studies in drug design.
Benefits
🔄 Reactive Functional Groups
The dimethylamino and ketone groups provide multiple sites for chemical modification, enhancing synthetic flexibility.
🧪 Intermediate Stability
The hydrochloride salt form improves stability and handling compared to the free base.
🌐 Versatile Scaffold
The thiophene ring imparts unique electronic properties useful in pharmaceuticals and materials chemistry.
🎯 Potential in CNS Drug Development
Compounds derived from this intermediate may exhibit activity in neurological disorders due to the pharmacologically relevant functional groups.
Conclusion
3-(Dimethylamino)-1-(thiophen-2-yl)propan-1-one hydrochloride (CAS 5424-47-5) is a valuable intermediate in pharmaceutical synthesis and organic chemistry. Its multifunctional structure allows for diverse applications in drug development, particularly in CNS-related therapies, and facilitates a wide range of synthetic transformations. This makes it an important compound in medicinal chemistry and advanced organic synthesis.
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