(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyric acid

(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyric acid is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyric acid (CAS 59554-14-2) is a chiral amino acid derivative widely used as an intermediate in pharmaceutical and peptide synthesis. Its primary applications include serving as a building block for the preparation of bioactive peptides, enzyme inhibitors, and therapeutic compounds where stereochemistry is crucial for biological activity. The compound's amino and hydroxyl functional groups allow for selective derivatization and coupling reactions, making it valuable in synthesizing complex molecules such as β-lactams, hydroxylated amino acids, and other nitrogen-containing bioactive frameworks.

The benefits of (2S,3R)-3-Amino-2-hydroxy-4-phenylbutyric acid arise from its stereochemical purity, chemical reactivity, and versatility in synthesis. Its defined (2S,3R) configuration ensures the production of enantiomerically pure compounds, which is essential for efficacy and safety in drug development. The presence of both amino and hydroxyl groups allows multiple chemical transformations, including peptide bond formation, acylation, and protection/deprotection strategies. Its stability and compatibility with standard organic solvents further enhance its suitability for laboratory and industrial-scale synthesis.

In conclusion, (2S,3R)-3-Amino-2-hydroxy-4-phenylbutyric acid is a valuable chiral intermediate for peptide synthesis, enzyme inhibitors, and pharmaceutical compounds. Its stereochemical integrity, functional versatility, and chemical stability enable efficient and selective synthesis of complex bioactive molecules. By supporting high-fidelity and scalable transformations, it plays a key role in modern medicinal chemistry and peptide development.

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