CAS · 511254-92-5
Product Overview
(2S)-1-Benzyl-2-methylpiperazine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Colorless or light yellow oil |
|---|---|
| Purity | 98% min |
| Optical Purity (ee) | 98% min |
Applications
(2S)-1-Benzyl-2-methylpiperazine is primarily used as an intermediate in pharmaceutical and medicinal chemistry. Its piperazine core, substituted with a benzyl group and a methyl group at the chiral center, allows it to participate in various alkylation, acylation, and coupling reactions. The compound is commonly applied in the synthesis of central nervous system agents, receptor modulators, and other bioactive molecules that require a chiral piperazine scaffold. It is also used in research and development for exploring structure-activity relationships, designing enantiomerically pure drug candidates, and constructing advanced intermediates in the preparation of therapeutic compounds.
Benefits
The benefits of (2S)-1-Benzyl-2-methylpiperazine stem from its chiral purity and functional versatility. The (2S)-configuration ensures predictable stereochemistry in downstream reactions, which is crucial for maintaining the desired biological activity in pharmaceuticals. Its benzyl-substituted piperazine ring provides a reactive site for further derivatization, allowing the introduction of diverse functional groups and structural modifications. The compound is chemically stable, easy to handle, and compatible with standard synthetic conditions, facilitating efficient multi-step synthesis. These characteristics make it a reliable and valuable building block for medicinal chemists seeking to develop complex, enantiomerically defined molecules.
Conclusion
(2S)-1-Benzyl-2-methylpiperazine is an important chiral intermediate for pharmaceutical and medicinal applications. Its applications in the synthesis of bioactive molecules and chiral drug candidates, together with benefits such as stereochemical integrity, versatility, and stability, make it a valuable tool in modern chemical and drug development. The compound enables efficient construction of advanced molecular scaffolds while supporting high-quality, reproducible synthesis of therapeutically relevant compounds.
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