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Product Line: Pharmaceutical Chemicals

2,4-Di-tert-butyl-5-nitrophenol

CAS 73-22-3

Molecular structure of 2,4-Di-tert-butyl-5-nitrophenol

CAS · 73-22-3

01

Product Overview

2,4-Di-tert-butyl-5-nitrophenol is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance Pale yellow to yellow solid
Identification by NMR To match with the reference standard
Assay (on dried basis) 97.0% min
Individual Impurity by HPLC 1.0% max
Total Impurities by HPLC 2.0% max
Water Content 0.5% max
Residue on Ignition 0.5% max
Loss on drying 0.5% max
03

Applications

2,4-Di-tert-butyl-5-nitrophenol is a functional phenolic compound widely used in polymer chemistry, material stabilization, and chemical research. It serves as a high-performance antioxidant and stabilizer in plastics, rubbers, resins, and lubricants, where it inhibits oxidative degradation and extends product lifespan. In polymer and resin production, it is applied to prevent discoloration, embrittlement, and loss of mechanical properties caused by heat, light, or oxygen exposure. The compound is also utilized as a building block for the synthesis of other functional phenolic derivatives, nitrophenols, and specialty chemicals in research and industrial applications. Its nitro and bulky tert-butyl substituents allow it to participate in selective reactions, making it useful in chemical intermediates development and structure–activity studies.

Benefits

The benefits of 2,4-Di-tert-butyl-5-nitrophenol stem from its strong antioxidant activity, thermal stability, and sterically hindered structure. The bulky tert-butyl groups protect the phenolic hydroxyl, providing resistance to oxidation and enhancing long-term stability in polymeric and high-temperature applications. Its nitro group contributes to chemical reactivity for functional derivatization and fine chemical synthesis. The compound is effective at low concentrations, reducing formulation costs while maintaining performance, and is compatible with a wide range of polymer matrices, oils, and solvents. Its stability under storage conditions ensures reliable performance and reproducibility in industrial and research processes.

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Benefits

The key benefits and differentiators of this product are available on request. Contact us for performance data, comparative specifications and selection guidance.

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Conclusion

2,4-Di-tert-butyl-5-nitrophenol is a versatile phenolic antioxidant and intermediate used in polymer stabilization, lubricant protection, and specialty chemical synthesis. Its combination of steric hindrance, chemical reactivity, and thermal stability allows effective inhibition of oxidative degradation and facilitates selective chemical transformations. By supporting long-lasting material performance and enabling functional derivative synthesis, this compound remains an important tool in modern polymer chemistry, materials science, and fine chemical research.

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