CAS · 421-53-4
Product Overview
2,2,2-trifluoroethane-1,1-diol is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Clear liquid |
|---|---|
| Purity | 75% min |
| Water | 25% max |
| Trifluoroethanol | 0.1% max |
Applications
2,2,2-Trifluoroethane-1,1-diol is primarily used as a specialized chemical intermediate in organic synthesis and pharmaceutical research. It serves as a building block for the preparation of fluorinated compounds, including agrochemicals, pharmaceuticals, and specialty materials. Its fluorinated diol structure allows selective reactions such as acylation, etherification, and condensation, making it valuable in the design of molecules with improved metabolic stability, lipophilicity, and bioactivity. It is also employed in the synthesis of polymeric materials and fine chemicals where fluorine incorporation is desired to enhance chemical and physical properties.
Benefits
The benefits of 2,2,2-trifluoroethane-1,1-diol include its ability to introduce trifluoromethyl groups into target molecules, improving chemical stability, lipophilicity, and bioavailability in pharmaceuticals and agrochemicals. Its diol functionality enables versatile derivatization, allowing incorporation into diverse molecular frameworks. The compound's reactivity, selectivity, and compatibility with various synthetic protocols make it an efficient intermediate for multi-step synthesis, supporting high yields and reproducibility. Its unique fluorinated properties also enhance performance in polymers and specialty materials.
Conclusion
2,2,2-Trifluoroethane-1,1-diol is a valuable fluorinated intermediate for pharmaceuticals, agrochemicals, and material science. Its combination of trifluoromethyl functionality and reactive diol groups allows versatile chemical modifications and improved molecular properties. By facilitating efficient synthesis and enhancing stability, bioavailability, and performance, this compound continues to play a significant role in advanced chemical and pharmaceutical applications.
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