CAS · 552-89-6
Product Overview
2-Nitrobenzaldehyde is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Off-white to light yellow powder or crystals |
|---|---|
| Purity | 99.0% min |
| Water content | 0.5% max |
| Impurities – 2-Nitrotoluene | 0.1% max |
| Impurities – 2-Nitrobenzyl alcohol | 1.0% max |
| Impurities – 3-Nitrobenzaldehyde | 0.2% max |
| Impurities – 4-Nitrobenzaldehyde | 0.2% max |
| Impurities – 2-Nitrobenzyl bromide | 0.2% max |
| Impurities – 2-Nitrobenzoic acid | 0.2% max |
| Other maximum single impurity | 0.5% max |
| Total impurities | 1.0% max |
| Residue on ignition | 0.5% max |
| Melting point | 41–44 °C |
Applications
2-Nitrobenzaldehyde is widely used as an important intermediate in organic synthesis, pharmaceutical research, and fine chemical production. It serves as a key building block for the synthesis of heterocyclic compounds, dyes, agrochemicals, and active pharmaceutical ingredients. The aldehyde group readily participates in condensation reactions such as Schiff base formation, Knoevenagel reactions, and cyclizations, while the nitro substituent enables further functional transformations, including reduction to amines. In medicinal chemistry, 2-nitrobenzaldehyde is used in the preparation of bioactive molecules and molecular probes. It is also applied in photochemistry and analytical research, where it can act as a photoreactive compound for studying light-induced reactions and molecular rearrangements.
Benefits
2-Nitrobenzaldehyde offers several advantages due to its dual functional groups and chemical reactivity. The presence of both a nitro group and an aldehyde function allows diverse and selective chemical modifications, supporting the efficient synthesis of structurally complex molecules. Its reactivity under mild conditions makes it suitable for multi-step synthetic pathways with good yields. The compound is chemically stable under standard storage conditions and compatible with a wide range of organic solvents, facilitating handling and process scalability. These properties make it a reliable and versatile intermediate for research laboratories and industrial applications.
Conclusion
2-Nitrobenzaldehyde is a versatile aromatic intermediate with broad applications in pharmaceuticals, agrochemicals, dyes, and advanced organic synthesis. Its benefits, including functional group versatility, controlled reactivity, and chemical stability, make it an essential building block for complex molecule construction. The compound continues to support innovation in medicinal chemistry, fine chemical manufacturing, and photochemical research.
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