CAS · 1450-85-7
Product Overview
2-Mercaptopyrimidine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White to yellow solid |
|---|---|
| Purity: | 98% min |
| Loss on drying: | 0.5% max |
| Single maximum impurity (unknown): | 0.5% max |
Applications
1. Pharmaceutical Intermediate
Acts as a key intermediate in the synthesis of pharmaceutical compounds, particularly antimicrobials, antivirals, and anticancer agents.
The thiol and pyrimidine functionalities serve as reactive handles in drug design.
2. Heterocyclic Chemistry
Frequently used in the construction of more complex heterocyclic systems.
It can undergo nucleophilic substitution, oxidation, and metal complexation reactions.
3. Coordination Chemistry & Ligand Design
The sulfur and nitrogen atoms make it a bidentate ligand for forming coordination complexes with transition metals.
Applications include catalysis, material science, and bioinorganic chemistry.
4. Corrosion Inhibition
Investigated as a corrosion inhibitor for metals (especially steel and copper) in acidic environments.
Forms a protective film via adsorption on metal surfaces.
5. Agrochemical Research
A useful building block for the synthesis of fungicides and plant growth regulators.
Incorporated in the development of pesticidal agents.
6. Analytical Reagent
Can be used as a reagent in analytical chemistry for the detection and quantification of certain metal ions due to its chelating nature.
Benefits
Versatile Functional Group: Contains both thiol and nitrogen donor atoms, offering a rich chemical reactivity profile.
Pharmacological Potential: Known for its bioactivity and potential in therapeutic agent development.
Metal Binding Affinity: Excellent complexation ability due to S and N atoms-useful in catalyst development and metal detection.
Small Molecular Weight: Useful as a scaffold for medicinal chemistry optimization.
Conclusion
2-Mercaptopyrimidine (CAS 1450-85-7) is a highly versatile compound prized for its utility in pharmaceutical synthesis, metal complexation, and corrosion inhibition. Its dual functional groups-thiol and pyrimidine-make it a powerful intermediate for developing biologically active molecules, metal-based catalysts, and specialty materials. As research into heterocyclic scaffolds and sulfur-containing drugs expands, the importance of this compound continues to grow.
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