CAS · 614-75-5
Product Overview
2-Hydroxyphenylacetic acid is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Light yellow to yellow powder |
|---|---|
| Content | 98% min |
| Melting point | 145–147°C |
| Water | 0.5% max |
Applications
2-Hydroxyphenylacetic acid (CAS 614-75-5) is an aromatic hydroxy acid used as an intermediate in pharmaceuticals, agrochemicals, and fine chemicals. Its structure, featuring both a phenolic hydroxyl group and a carboxylic acid, makes it useful for synthesizing esters, amides, and heterocycles. In pharmaceuticals, it serves as a precursor for anti-inflammatory agents, analgesics, and other bioactive compounds. In agrochemicals, it is applied in the preparation of herbicides and fungicides where hydroxyphenyl motifs enhance activity. It is also employed in the fragrance and flavor industry for synthesizing aromatic derivatives with sweet or floral notes, and in polymer chemistry where it can be incorporated into specialty resins and monomers.
Benefits
The benefits of 2-hydroxyphenylacetic acid lie in its dual functional groups and chemical versatility. The phenolic hydroxyl enables selective reactions such as etherification, acylation, and oxidative coupling, while the carboxyl group undergoes esterification, amidation, or salt formation. This dual reactivity allows chemists to design complex molecules efficiently, reducing synthetic steps. Its aromatic structure provides stability, while the hydroxyl group enhances solubility and binding affinity in bioactive molecules. Together, these features make it a valuable intermediate for producing pharmaceuticals, agrochemicals, fragrances, and specialty chemicals with high functionality and stability.
Conclusion
In summary, 2-hydroxyphenylacetic acid is a multifunctional intermediate applied in pharmaceuticals, agrochemicals, fragrances, and specialty polymers. Its applications include drug precursors, crop-protection agents, aromatic derivatives, and resin components, while its benefits come from versatile reactivity, structural stability, and efficiency in synthetic pathways. As industries continue to demand functional aromatic intermediates, 2-hydroxyphenylacetic acid remains an important building block for innovation in chemical synthesis.
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