2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid
CAS 763114-26-7
CAS · 763114-26-7
Product Overview
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Characteristics | Off-white powder |
|---|---|
| Purity (HPLC) | 98% min |
| Single impurity | 0.2% max |
| Total impurities | 0.2% max |
| Water (K.F.) | 0.5% max |
| Residue on ignition | 0.2% max |
Applications
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid is primarily used as a key intermediate in pharmaceutical research and drug development. It is valuable for the synthesis of bioactive compounds, particularly those targeting cardiovascular, anti-inflammatory, or anticancer pathways. The molecule's fluoro-substituted benzoic acid moiety enables enhanced pharmacokinetic properties, while the dihydrophthalazinone scaffold contributes to binding affinity in medicinal chemistry. It is also employed in structure-activity relationship (SAR) studies to develop novel therapeutic candidates and optimize lead compounds.
Benefits
The compound provides several benefits in drug discovery and medicinal chemistry. Its fluorine substitution enhances metabolic stability and bioavailability, improving the pharmacological profile of derivative molecules. The dihydrophthalazinone framework offers rigidity and favorable electronic properties, supporting high-affinity interactions with biological targets. Additionally, the combination of reactive functional groups allows for selective chemical modifications, facilitating multi-step synthesis and optimization of bioactive molecules. These properties make it a reliable intermediate for designing potent and stable pharmaceutical candidates.
Conclusion
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid is an important pharmaceutical intermediate that enables the development of novel therapeutics. Its fluorinated benzoic acid and dihydrophthalazinone scaffold provide chemical versatility, improved stability, and enhanced bioactivity. The compound's role in medicinal chemistry supports efficient lead optimization, structure-activity studies, and the creation of high-performance drug candidates.
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