CAS · 89-98-5
Product Overview
2-Chlorobenzaldehyde is a high-purity pesticide-intermediate supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Colorless liquid |
|---|---|
| Assay | 99% min |
| Water | 0.2% max |
| 2-Chlorotoluene | 0.2% max |
| 2-Chlorobenzyl chloride | 0.3% max |
| 3-Chlorobenzal chloride | 0.2% max |
| Other impurities | 0.3% max |
Applications
1. Pharmaceutical Intermediate
2-Chlorobenzaldehyde is widely used as a building block in the synthesis of various pharmaceutical compounds.
It is a precursor for benzodiazepines, antibacterial agents, antihistamines, and anticancer compounds.
Its reactive aldehyde group allows it to undergo condensation and cyclization reactions used in heterocyclic compound synthesis.
2. Agrochemical Synthesis
Serves as an intermediate in the production of fungicides, herbicides, and insecticides.
It is used to prepare active ingredients in crop protection chemicals through aldol condensations and halogen substitutions.
3. Dye and Pigment Industry
Used in the synthesis of azo dyes and anthraquinone dyes.
Its aromatic structure and functional groups enable coupling with amines and other chromophores for producing colorants.
4. Flavor and Fragrance Intermediates
Although not directly used due to its strong odor, it serves as an intermediate in the synthesis of fragrance compounds or masking agents.
Can be transformed into derivatives with more pleasant olfactory properties.
5. Polymer and Material Science
Used in the functionalization of polymers or monomer synthesis where aromatic aldehydes are needed.
Its incorporation in polymer backbones can impart UV resistance or chemical reactivity for further cross-linking.
6. Research and Development
In academic and industrial research, 2-chlorobenzaldehyde is used in the development of:
Heterocycles (e.g., quinolines, indoles, imidazoles)
Ligands for metal complexes
Fine chemicals and custom molecules for medicinal chemistry studies.
Benefits
Dual Functionality: Combines a reactive aldehyde group and an electrophilic halogen, enabling a wide variety of transformations including Grignard reactions, reductions, and nucleophilic aromatic substitutions.
Versatile Intermediate: Its ortho-substitution pattern allows for the formation of ring-closed or fused structures useful in drug development.
Industrial Utility: Offers high yields in coupling and condensation reactions, supporting scalable manufacturing processes.
Cost-Effective: Readily available commercially and relatively inexpensive, making it suitable for bulk chemical production.
Stable Under Ambient Conditions: Can be stored and handled with standard precautions, increasing convenience in industrial and lab environments.
Conclusion
2-Chlorobenzaldehyde (CAS 89-98-5) is a highly useful intermediate in the chemical industry due to its unique combination of aldehyde reactivity and chlorine substitution. Its primary applications span across pharmaceuticals, agrochemicals, dyes, and materials science, where it enables the efficient synthesis of complex organic molecules. With broad utility and functional adaptability, 2-chlorobenzaldehyde continues to play an important role in organic synthesis and industrial chemistry.
Previous
2-Chloro-5-chloromethylthiazole丨CAS 105827-91-6
Next