CAS · 5061-21-2
Product Overview
2-Bromo-4-butanolide is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Characteristics | Colorless to light yellow clear liquid |
|---|---|
| Assay (GC) | 98% min |
| Water | 0.2% max |
| Single impurity | 0.5% max |
| Specific impurity | 0.3% max |
Applications
2-Bromo-4-butanolide is a versatile organic intermediate widely used in pharmaceutical, agrochemical, and fine chemical synthesis. Its lactone ring with a bromine substituent makes it a valuable building block for preparing heterocycles, bioactive compounds, and functionalized molecules. In medicinal chemistry, it is utilized in the synthesis of potential drug candidates, especially those targeting enzyme inhibition or possessing antimicrobial and anticancer properties. In agrochemistry, it serves as a precursor for pesticide and herbicide development due to its reactive lactone functionality. Additionally, 2-bromo-4-butanolide is applied in synthetic organic chemistry as a reagent for ring-opening reactions, substitution, and further derivatization to produce structurally complex compounds.
Benefits
The benefits of 2-bromo-4-butanolide lie in its multifunctional reactivity, stability, and adaptability in synthetic processes. Its bromine atom provides a good leaving group, enabling efficient nucleophilic substitution and coupling reactions, while the lactone ring allows further transformation into diverse functional groups. This dual functionality makes it a highly flexible intermediate, reducing the number of steps required in multistage syntheses. The compound is also relatively stable under standard storage conditions yet reactive enough for controlled transformations, making it reliable for laboratory and industrial applications. Its adaptability in producing complex molecules adds significant value in pharmaceutical research, agrochemical development, and fine chemical production.
Conclusion
In conclusion, 2-bromo-4-butanolide is an important synthetic intermediate with applications in pharmaceuticals, agrochemicals, and advanced organic synthesis. Its benefits include dual functional reactivity, stability, and efficiency in constructing complex molecular architectures. By combining structural versatility with practical reliability, 2-bromo-4-butanolide continues to be a valuable compound in chemical research and industrial development.
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