CAS · 5345-47-1
Product Overview
2-Aminonicotinic acid is a high-purity amino-acids supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Off White powder |
|---|---|
| Assay (HPLC): | 98% min |
| Loss on drying: | 0.5% max |
| Any other impurity (HPLC): | 1% max |
Applications
1. Pharmaceutical Intermediate
Commonly used in the synthesis of active pharmaceutical ingredients (APIs).
Serves as a building block for various heterocyclic compounds.
Used in drug discovery for anti-inflammatory, antibacterial, or anticancer agents due to its pyridine-based structure.
2. Ligand in Coordination Chemistry
Acts as a bidentate ligand, coordinating through the amino and carboxylic groups.
Used to form metal-organic complexes, especially with transition metals (e.g., Cu, Fe, Zn), which are studied for catalytic, magnetic, or biological properties.
3. Organic Synthesis
Useful intermediate for synthesizing:
Pyridine derivatives
Heterocyclic compounds
Functionalized azo dyes or polymers
4. Agrochemical Research
Investigated as a precursor for synthesizing biologically active compounds such as plant growth regulators, fungicides, or herbicides.
5. Analytical Chemistry
May be employed in the development of complexometric titrants or chelating agents for metal ion detection or separation.
Benefits
Dual Functional Groups: Its amino and carboxylic acid moieties provide multiple points of reactivity for chemical derivatization.
Good Water Solubility: Facilitates its use in aqueous-based synthesis and biological testing.
Versatility: Widely applicable in drug design, materials science, and coordination chemistry.
Structural Simplicity: Makes it a suitable core for modifications in structure-activity relationship (SAR) studies.
Conclusion
2-Aminonicotinic acid (CAS 5345-47-1) is a valuable heterocyclic compound widely used in pharmaceutical research, metal coordination chemistry, and organic synthesis. Its bifunctional nature and pyridine ring make it highly versatile and reactive, supporting a range of applications from drug development to materials science.
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