CAS · 2011-66-7
Product Overview
2-Amino-2-chloro-5-nitro benzophenone is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Yellow crystalline powder |
|---|---|
| Purity: | 99% min |
| Melting point: | 118-120°C |
| Loss on drying: | 0.5% max |
Applications
2-Amino-2-chloro-5-nitrobenzophenone is a halogenated aromatic ketone widely used as an intermediate in pharmaceutical, dye, and fine chemical synthesis. Its amino, chloro, and nitro functionalities enable diverse chemical transformations, including nucleophilic substitution, reduction, and condensation reactions, allowing the synthesis of heterocyclic compounds, bioactive molecules, and specialty dyes. In medicinal chemistry, it serves as a building block for enzyme inhibitors, antiviral agents, and other pharmacologically active derivatives. The ketone group provides a reactive site for condensation and coupling reactions, while the halogen and nitro substituents allow selective functionalization, making it valuable for structure–activity relationship (SAR) studies and the development of novel bioactive compounds.
Benefits
The benefits of 2-Amino-2-chloro-5-nitrobenzophenone are linked to its multifunctional reactivity, chemical stability, and synthetic versatility. The amino group allows derivatization into amides, imines, or azo compounds, while the chloro substituent provides a reactive site for palladium- or copper-mediated cross-coupling reactions. The nitro group can be selectively reduced to amines or converted into other functional groups, enabling multi-step synthetic pathways. Its ketone functionality facilitates condensation, nucleophilic addition, and cyclization reactions. These features, combined with high purity and reproducibility, make it suitable for laboratory research and industrial-scale synthesis of complex molecules and functional intermediates.
Conclusion
2-Amino-2-chloro-5-nitrobenzophenone is a versatile halogenated aromatic ketone intermediate with broad applications in pharmaceuticals, dyes, and fine chemicals. Its combination of amino, chloro, nitro, and ketone functionalities allows efficient and selective chemical transformations, supporting the synthesis of bioactive molecules, heterocycles, and specialty compounds. By enabling structural diversification and multi-step synthesis, it remains an essential building block in medicinal chemistry and advanced organic synthesis.
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