CAS · 2871-01-4
Product Overview
2-(4-Amino-2-nitroanilino)-ethanol is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Black-green to Blackish green Crystal powder |
|---|---|
| Purity (HPLC) | 98% min |
| Loss on drying | 1.0% max |
| Fe | 50 ppm max |
| Ash | 1.0% max |
Applications
1. Intermediate in Dye and Pigment Synthesis
Widely used as a key intermediate in the manufacture of:
Disperse dyes
Reactive dyes
Acid dyes
Its electron-donating amino and electron-withdrawing nitro groups facilitate azo coupling, making it suitable for producing vibrant yellow, red, and orange dyes for polyester and synthetic fibers.
2. Colorant Manufacturing
Forms the base for azo dyes, which are essential for:
Textile dyeing
Inks for inkjet printers
Leather dyeing
The hydroxyl-ethyl group enhances water solubility or reactivity of resulting dyes, improving fiber affinity and fixation.
3. Pharmaceutical Research Intermediate
Due to the presence of amino, nitro, and hydroxyl groups, this molecule can serve in the synthesis of heterocyclic compounds and bioactive intermediates.
Potential precursor for antimicrobial, antiparasitic, or anticancer compound development in early-stage medicinal chemistry.
4. Chemical Linker or Ligand
The ethanol and amino functionalities allow this compound to act as a ligand or crosslinking agent in:
Coordination chemistry
Polymer functionalization
Metal-dye complexes
5. Research Use
Frequently utilized in structure–activity relationship (SAR) studies and analytical method development.
Can be derivatized to study its electron transfer or chromophore behavior under UV-vis spectroscopy.
Benefits
✅ Multifunctional Reactivity
Contains nucleophilic (-NH₂, -OH) and electrophilic (-NO₂) groups, enabling a wide variety of chemical reactions:
Azo coupling
Esterification
Etherification
Reduction to diamines
✅ Excellent Intermediate for Azo Dye Synthesis
Highly reactive toward diazonium salts, making it ideal for constructing azo bonds-the basis of many synthetic dyes.
✅ Improved Solubility and Reactivity
The ethanol group enhances the hydrophilicity and provides sites for further modification or conjugation.
✅ Customizable Chromophore System
Can be used to build tailored chromophores with tunable absorption characteristics for various industrial and scientific uses.
Conclusion
2-(4-Amino-2-nitroanilino)-ethanol (CAS 2871-01-4) is a versatile intermediate mainly used in dye manufacturing, especially azo and disperse dyes for textiles and polymers. Its multifunctional structure also lends itself to applications in pharmaceutical R&D, ligand design, and analytical chemistry. With a unique combination of amine, nitro, and hydroxyl groups, it provides both chemical flexibility and enhanced reactivity, making it valuable in both industrial and laboratory settings.
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