CAS · 63-89-8
Product Overview
1,2-Dipalmitoyl-sn-glycero-3-phosphocholine is a high-purity biochemical-reagents supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | white solid |
|---|---|
| Purity(HPLC) | 99% min |
| Clarity | clear and transparent (50mg in 1ml trichloromethane) |
Applications
1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) is a major phospholipid widely used in pharmaceutical formulations, biomedical research, and materials science. It is the principal component of pulmonary surfactant and is therefore extensively applied in respiratory research, reconstituted surfactant systems, and drug-delivery formulations targeting the lungs. In liposome and nanoparticle technology, DPPC is used to prepare stable bilayer membranes for encapsulation of hydrophilic and hydrophobic drugs, enhancing controlled release and improving bioavailability. It is also used in membrane biophysics studies to model biological membranes due to its well-characterized phase transition properties. Beyond pharmaceuticals, DPPC is implemented in cosmetics, biochemical assays, and surface-modification technologies to improve biocompatibility and create bio-mimetic interfaces.
Benefits
The benefits of DPPC stem from its excellent biocompatibility, structural stability, and well-defined physicochemical behavior. Its saturated fatty acid chains confer high membrane rigidity and predictable phase transition behavior, making it ideal for studying model membranes and designing stable liposomes with controlled leakage profiles. In drug delivery, DPPC contributes to enhanced stability of lipid-based carriers and can improve therapeutic index by supporting targeted or sustained release. Its biological relevance-being a dominant component of natural lung surfactant-makes it suitable for respiratory formulations and biophysical research involving surface tension reduction. Additionally, DPPC is non-toxic, reproducible in performance, and compatible with a wide range of formulation conditions, enabling use in both laboratory and clinical-oriented material development.
Conclusion
1,2-Dipalmitoyl-sn-glycero-3-phosphocholine is a versatile, highly biocompatible phospholipid with extensive applications in drug delivery, membrane modeling, surfactant systems, and biomedical materials. Its structural stability, predictable thermotropic properties, and physiological relevance make it indispensable in both research and applied formulation science. By supporting controlled release, enhancing biocompatibility, and mimicking natural membrane environments, DPPC plays a key role in advancing pharmaceutical technologies and membrane-based studies.
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