1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine is a high-purity biochemical-reagents supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (CAS 26662-94-2), often abbreviated as POPE, is a glycerophospholipid widely used in biochemical and biophysical research. It is a major component of biological membranes and is employed in the preparation of model membranes, liposomes, and lipid bilayers for studying membrane dynamics, permeability, and protein–lipid interactions. POPE is extensively applied in structural biology to reconstitute membrane proteins, providing a native-like environment for functional and mechanistic studies. It is also used in drug delivery research, where it forms part of lipid-based carriers for controlled release of therapeutic agents. In addition, POPE is relevant in synthetic biology, nanotechnology, and materials science, supporting the design of biomimetic systems and functional nanostructures.

The benefits of POPE lie in its ability to mimic natural membrane environments and support biological functionality in experimental systems. Its amphiphilic structure allows it to form stable bilayers and liposomes, making it indispensable for studying cellular processes under physiologically relevant conditions. The presence of both saturated (palmitoyl) and unsaturated (oleoyl) fatty acid chains provides a balance of membrane fluidity and stability, closely resembling biological membranes. In research, this enables accurate exploration of membrane protein folding, signaling, and drug–membrane interactions. From a practical standpoint, POPE enhances reproducibility in experimental setups and contributes to the development of advanced drug delivery platforms. Its role in bridging molecular biology, medicine, and nanotechnology underscores its value as a versatile and reliable lipid.

In conclusion, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine is a vital phospholipid applied across membrane biology, pharmaceutical research, and nanotechnology. Its applications include membrane modeling, protein reconstitution, and drug delivery systems, while its benefits center on biological relevance, membrane stability, and experimental reliability. As research in biomedicine and nanoscience advances, POPE remains an essential tool for exploring cellular processes and developing innovative therapeutic and biomimetic solutions.

Previous

Dierucoyl Phosphatidylcholine丨CAS 4235-95-4

Next

Harringtonin丨CAS 26833-85-2