1-Chlorocarbonyl-4-piperidinopiperidine hydrochloride
CAS 143254-82-4
CAS · 143254-82-4
Product Overview
1-Chlorocarbonyl-4-piperidinopiperidine hydrochloride is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White or white crystalline powder |
|---|---|
| Purity (GC) | 98% min |
| Assay | 97% min |
| Identification (GC) | GC retention time of sample should be concordant with that of reference |
| Water | 1.0% max |
| Ignition residue | 0.3% max |
| Max individual impurity | 1.0% max |
Applications
1-Chlorocarbonyl-4-piperidinopiperidine hydrochloride is mainly used as a specialized intermediate for the synthesis of complex pharmaceutical candidates and research molecules. Its combination of a piperidine-based heterocycle and a reactive chlorocarbonyl group enables the construction of ureas, carbamates, amide bonds, and related structural motifs that are important in medicinal chemistry. It is applied in structure–activity relationship programs, the preparation of screening-library compounds, and the development of chemical probes. The compound also plays a role in custom fine-chemical synthesis, bioactive molecule development, and heterocycle functionalization, where selective acylation or coupling steps are required.
Benefits
This compound offers strong benefits due to its high reactivity and functional versatility, supporting efficient formation of carbonyl-linked structures with a broad range of nucleophiles. The hydrochloride salt form provides enhanced stability, easier handling, and improved solubility in common polar solvents, which simplifies storage and workup. Its piperidine-based framework integrates smoothly into pharmaceutical scaffolds, often reducing the number of reaction steps and minimizing the need for protecting-group strategies. The compound also demonstrates predictable and reproducible reaction behavior, allowing chemists to design reliable synthetic routes for advanced heterocycles and other complex intermediates.
Conclusion
1-Chlorocarbonyl-4-piperidinopiperidine hydrochloride serves as a valuable building block for medicinal chemistry, organic synthesis, and fine-chemical research. Its combination of structural complexity, reactive functionality, and practical handling characteristics makes it a versatile intermediate that supports efficient development of diverse chemical entities.
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