CAS · 431-37-8
Product Overview
1-Chloro-3,3,3-trifluoroacetone is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Colorless or light yellowish transparent liquid |
|---|---|
| Purity | 97% min |
| Identification (GC-MS) | Conforms |
| Identification (HNMR) | Conforms |
Applications
1-Chloro-3,3,3-trifluoroacetone is widely used as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty fluorinated compounds. It serves as a building block for the preparation of trifluoromethyl ketones, heterocyclic compounds, and fluorinated analogs of bioactive molecules. The compound is also employed in research and development for the design of enzyme inhibitors and in the production of materials that require enhanced chemical or thermal stability.
Benefits
This compound offers high reactivity due to both the carbonyl and chloro functional groups, allowing efficient nucleophilic substitution and condensation reactions. The trifluoromethyl group imparts enhanced chemical and metabolic stability to downstream products, improving their performance in pharmaceuticals and agrochemicals. Its versatility in synthetic transformations and predictable behavior under controlled conditions make it a valuable intermediate in fine chemical synthesis.
Conclusion
1-Chloro-3,3,3-trifluoroacetone is a highly functional and versatile intermediate that enables the synthesis of fluorinated pharmaceuticals, agrochemicals, and specialty materials. Its reactivity, stability, and applicability in advanced chemical processes make it an essential building block in modern synthetic chemistry.
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