CAS · 72934-37-3
Product Overview
1-(4-Chlorophenyl)cyclopropanecarboxylic acid is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Off-white or white powder |
|---|---|
| Purity: | 98% min |
Applications
1-(4-Chlorophenyl)cyclopropanecarboxylic acid (CAS 72934-37-3) is an aromatic cyclopropane derivative commonly used as an intermediate in pharmaceutical and agrochemical synthesis. Its cyclopropane carboxylic acid moiety and para-chlorophenyl substitution make it a versatile building block for the preparation of bioactive molecules, including enzyme inhibitors, receptor modulators, and other therapeutic candidates. It is also employed in the design of agrochemicals such as herbicides, fungicides, and insecticides, where the chlorophenyl group enhances chemical stability and biological activity. Additionally, it serves as a precursor for further functionalization, including amide formation, esterification, and cyclization reactions, facilitating the synthesis of structurally diverse compounds.
Benefits
The benefits of 1-(4-chlorophenyl)cyclopropanecarboxylic acid derive from its reactive carboxylic acid group and rigid cyclopropane ring, which provide structural stability and synthetic flexibility. The para-chloro substitution enhances lipophilicity, metabolic stability, and binding affinity in bioactive derivatives. Its carboxyl functionality allows for straightforward derivatization into amides, esters, or other functional groups, enabling the construction of a wide variety of molecules with tailored properties. The combination of chemical stability, reactivity, and steric rigidity makes it an efficient and reliable intermediate for pharmaceutical and agrochemical development.
Conclusion
1-(4-Chlorophenyl)cyclopropanecarboxylic acid is a versatile intermediate with significant applications in pharmaceuticals, agrochemicals, and fine chemical synthesis. Its cyclopropane carboxylic acid structure, combined with para-chlorophenyl substitution, provides stability, reactivity, and functional versatility. By enabling efficient synthesis of bioactive and chemically robust molecules, it remains an important tool in chemical research and industrial applications.
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