CAS · 247940-06-3
Product Overview
2-(Dicyclohexylphosphino)biphenyl is a high-purity organophosphorus-compounds supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Off-white or white solid |
|---|---|
| Assay | 98% min |
| Melting Point (MP) | 101 to 104 °C |
Applications
2-(Dicyclohexylphosphino)biphenyl is a bulky, electron-rich phosphine ligand extensively used in homogeneous catalysis. It is a key component in palladium-catalyzed cross-coupling reactions, such as Suzuki–Miyaura, Buchwald–Hartwig amination, and Heck reactions, enabling the efficient formation of carbon–carbon and carbon–heteroatom bonds. The ligand is also employed in the synthesis of fine chemicals, pharmaceuticals, and agrochemicals, where high selectivity and catalytic efficiency are required. Additionally, it is utilized in academic and industrial research to develop new catalytic systems and optimize reaction conditions for complex organic transformations.
Benefits
The benefits of this ligand arise from its steric bulk and electron-donating properties, which enhance the activity, stability, and selectivity of metal catalysts. Its rigid biphenyl backbone provides a well-defined coordination environment for transition metals, improving catalyst lifetime and turnover. The ligand allows for mild reaction conditions, high yields, and reduced side reactions, making it highly valuable in pharmaceutical and fine chemical synthesis. Furthermore, its compatibility with a wide range of solvents and substrates ensures versatility in various catalytic applications.
Conclusion
2-(Dicyclohexylphosphino)biphenyl is a powerful phosphine ligand used in palladium-catalyzed cross-coupling and other catalytic reactions. Its benefits include enhanced catalytic activity, selectivity, stability, and broad applicability in organic synthesis. By facilitating efficient formation of C–C and C–heteroatom bonds, it remains a crucial tool for industrial and research applications in fine chemicals, pharmaceuticals, and advanced materials.
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2-(Dicyclohexylphosphino)-N2,N2,N6,N6-tetramethyl1,1-biphenyl-2,6-diamine丨CAS 1160556-64-8
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