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2-Difluoromethanesulfonylpyridine

CAS 1219454-89-3

Molecular structure of 2-Difluoromethanesulfonylpyridine

CAS · 1219454-89-3

01

Product Overview

2-Difluoromethanesulfonylpyridine is a high-purity fluorine supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance Off-white crystals
Purity 98% min
03

Applications

2-Difluoromethanesulfonylpyridine is a specialized heterocyclic compound used primarily as an intermediate in pharmaceutical and agrochemical synthesis. It is applied in the development of bioactive molecules, where the pyridine core and difluoromethanesulfonyl group enhance metabolic stability, lipophilicity, and binding affinity. The compound is also employed in medicinal chemistry research to design enzyme inhibitors, receptor modulators, and other targeted therapeutics. Additionally, it serves as a versatile building block for the synthesis of fluorinated derivatives in fine chemical and material science applications.

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Benefits

The benefits of this compound include its chemical stability, reactivity, and ability to modulate electronic properties in target molecules. The difluoromethanesulfonyl group provides strong electron-withdrawing effects, improving biological activity and selectivity in drug candidates. Its pyridine scaffold supports structural rigidity and facilitates further functionalization, allowing the design of diverse derivatives. Furthermore, it is compatible with common organic reactions, including cross-coupling and nucleophilic substitution, enabling efficient synthesis of complex molecules.

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Conclusion

2-Difluoromethanesulfonylpyridine is a valuable intermediate in pharmaceutical, agrochemical, and fine chemical research. Its benefits include chemical stability, electronic modulation, and synthetic versatility, making it an essential building block for the development of bioactive and fluorinated compounds.

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