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Hoffer’s chlorosugar

CAS 4330-21-6

Molecular structure of Hoffer’s chlorosugar

CAS · 4330-21-6

01

Product Overview

Hoffer’s chlorosugar is a high-purity biochemical-reagents supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance off white powder
Purity 95% min
Loss on drying 2.0% max
Residue on Ignition 0.5% max
03

Applications

Hoffer's chlorosugar is primarily used as a key intermediate in carbohydrate chemistry and glycoside synthesis. It serves as a versatile building block for preparing various protected sugar derivatives, glycosyl donors, and analogs in the synthesis of complex oligosaccharides, glycoconjugates, and natural products. The compound is widely employed in medicinal chemistry for designing carbohydrate-based drugs and vaccines, as well as in chemical biology to study carbohydrate–protein interactions. Additionally, it finds use in the preparation of stereochemically defined sugar molecules essential for enzymatic and synthetic applications.

04

Benefits

Hoffer's chlorosugar offers high stereochemical control and reactivity, enabling selective glycosylation reactions under mild conditions. Its chlorinated functionality facilitates the formation of glycosidic bonds with excellent yield and regioselectivity. This intermediate simplifies the synthesis of complex sugars and glycoconjugates by reducing the number of protection/deprotection steps. Its use accelerates research in carbohydrate-based therapeutics and diagnostics by providing reliable access to structurally precise sugar building blocks.

05

Conclusion

Hoffer's chlorosugar is a crucial intermediate in carbohydrate synthesis, enabling efficient and selective construction of complex sugar molecules. Its stereochemical precision and reactivity support advances in drug discovery, vaccine development, and chemical biology, making it indispensable for modern carbohydrate chemistry.

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